The rise of Candida auris: from unique traits to co-infection potential
Cancer immunotherapy, which use the own immune system to attack tumors, are increasingly popular treatments. But, due to the tumor immunosuppressive microenvironment, the antigen presentation in the tumor is limited. Recently, a growing number of people use bacteria to stimulate the body’s immunity...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Shared Science Publishers OG
2022-08-01
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| Series: | Microbial Cell |
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| Online Access: | http://microbialcell.com/researcharticles/2022a-xu-microbial-cell/ |
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| _version_ | 1850053115306311680 |
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| author | Haiheng Xu Yiqiao Hu Jinhui Wu |
| author_facet | Haiheng Xu Yiqiao Hu Jinhui Wu |
| author_sort | Haiheng Xu |
| collection | DOAJ |
| description | Cancer immunotherapy, which use the own immune system to attack tumors, are increasingly popular treatments. But, due to the tumor immunosuppressive microenvironment, the antigen presentation in the tumor is limited. Recently, a growing number of people use bacteria to stimulate the body’s immunity for tumor treatment due to bacteria themselves have a variety of elements that activate Toll-like receptors. Here, we discuss the use of motility of flagellate bacteria to transport antigens to the tumor periphery to activate peritumoral dendritic cells to enhance the effect of in situ tumor vaccines. |
| format | Article |
| id | doaj-art-fd7eaf474f22492787a0b09e976fa34f |
| institution | DOAJ |
| issn | 2311-2638 |
| language | English |
| publishDate | 2022-08-01 |
| publisher | Shared Science Publishers OG |
| record_format | Article |
| series | Microbial Cell |
| spelling | doaj-art-fd7eaf474f22492787a0b09e976fa34f2025-08-20T02:52:37ZengShared Science Publishers OGMicrobial Cell2311-26382022-08-019915816110.15698/mic2022.09.784The rise of Candida auris: from unique traits to co-infection potentialHaiheng Xu0Yiqiao Hu1Jinhui Wu2State Key Laboratory of Pharmaceutical Biotechnology, Medical School of Nanjing University & School of Life Sciences, Nanjing University, Nanjing 210093, China.State Key Laboratory of Pharmaceutical Biotechnology, Medical School of Nanjing University & School of Life Sciences, Nanjing University, Nanjing 210093, China.State Key Laboratory of Pharmaceutical Biotechnology, Medical School of Nanjing University & School of Life Sciences, Nanjing University, Nanjing 210093, China.Cancer immunotherapy, which use the own immune system to attack tumors, are increasingly popular treatments. But, due to the tumor immunosuppressive microenvironment, the antigen presentation in the tumor is limited. Recently, a growing number of people use bacteria to stimulate the body’s immunity for tumor treatment due to bacteria themselves have a variety of elements that activate Toll-like receptors. Here, we discuss the use of motility of flagellate bacteria to transport antigens to the tumor periphery to activate peritumoral dendritic cells to enhance the effect of in situ tumor vaccines.http://microbialcell.com/researcharticles/2022a-xu-microbial-cell/flagellate bacteriaantigen presentationtransport antigentumor vaccinetumor peripherydendritic cellabscopal effect |
| spellingShingle | Haiheng Xu Yiqiao Hu Jinhui Wu The rise of Candida auris: from unique traits to co-infection potential Microbial Cell flagellate bacteria antigen presentation transport antigen tumor vaccine tumor periphery dendritic cell abscopal effect |
| title | The rise of Candida auris: from unique traits to co-infection potential |
| title_full | The rise of Candida auris: from unique traits to co-infection potential |
| title_fullStr | The rise of Candida auris: from unique traits to co-infection potential |
| title_full_unstemmed | The rise of Candida auris: from unique traits to co-infection potential |
| title_short | The rise of Candida auris: from unique traits to co-infection potential |
| title_sort | rise of candida auris from unique traits to co infection potential |
| topic | flagellate bacteria antigen presentation transport antigen tumor vaccine tumor periphery dendritic cell abscopal effect |
| url | http://microbialcell.com/researcharticles/2022a-xu-microbial-cell/ |
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