Transforming growth factor-βeta and interleukin-1βeta in children with acute liver failure: pathophysiology and outcome perspectives

Transforming growth factor-βeta and interleukin-1βeta in children with acute liver failure: pathophysiology and outcome perspectives

Abstract Background The exact pathophysiology of acute liver failure (ALF) in children is not well defined. Some animal studies showed increased cytokines as a driving force for its occurrence with defective similar human studies. This study aimed to measure the plasma level of the pro-inflammatory...

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Bibliographic Details
Main Authors: Mohammed Abdel-Salam El-Guindi, Sara Mohammed Abdel Ghafar El Taras, Samar Ebrahim Ghanem, Ahmad Mohamed Sira, Samira Abdel-Wahab Abdel-Aziz
Format: Article
Language:English
Published: SpringerOpen 2025-03-01
Series:Egyptian Liver Journal
Subjects:
Acute liver failure
Pro-inflamatory
Anti-inflamatory cytokines
Transforming growth factor-β
Interleukin-1β
Online Access:https://doi.org/10.1186/s43066-025-00409-z
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