Bibliometric analysis of monoclonal antibodies for atherosclerosis

Atherosclerosis (AS) is a prevalent cardiovascular disease that greatly increases mortality in the aging population and imposes a heavy burden on global healthcare systems. The purpose of this study is to examine the research structure and current trends of monoclonal antibodies (mAbs) against AS fr...

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Main Authors: Jiqing Ma, Kaiwen Zhao, Yalin Zhu, Wen Xu, Jie Huang, Xiaolong Wei, Zhiqing Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2023.2266926
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author Jiqing Ma
Kaiwen Zhao
Yalin Zhu
Wen Xu
Jie Huang
Xiaolong Wei
Zhiqing Zhao
author_facet Jiqing Ma
Kaiwen Zhao
Yalin Zhu
Wen Xu
Jie Huang
Xiaolong Wei
Zhiqing Zhao
author_sort Jiqing Ma
collection DOAJ
description Atherosclerosis (AS) is a prevalent cardiovascular disease that greatly increases mortality in the aging population and imposes a heavy burden on global healthcare systems. The purpose of this study is to examine the research structure and current trends of monoclonal antibodies (mAbs) against AS from a bibliometric perspective, since the development of these drugs is currently booming. This study collected articles and reviews on mAbs against AS from the Web of Science Core Collection, spanning from 2003 to 2022. Biblioshiny was utilized to analyze and visualize the characteristics of countries, regions, authors, institutions, and journals included in this collection. We used VOS viewer to illustrate the frequency of country co-occurrence, and CiteSpace to visualize co-cited reference, keywords co-occurrence, keywords citation bursts, keywords clustering and timeline plots. The study included 1325 publications, with the United States emerging as a leading contributor to the field. ATHEROSCLEROSIS, CIRCULATION and ARTERIOSCLEROSISTHROMBOSIS AND VASCULAR BIOLOGY are core journals that publish high-quality literature on the latest advances in the field. Noteworthy authors with numerous high-quality publications include Witztum JL and Tsimikas S. Currently, lipid metabolism and inflammation are the main research areas of interest in this field. The mAbs against AS is an evolving field, and ongoing research continues to advance our understanding. This paper provides a comprehensive overview of the current state of knowledge in this area, highlighting two primary research directions: inflammation and lipid metabolism. Additionally, the paper identifies emerging research hotspots, which will provide researchers with useful insights to guide future investigations and anticipate research directions.
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spelling doaj-art-fd77efb5d4f6432b9310f4c1fab0c0e22025-08-20T03:26:39ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2023-12-0119310.1080/21645515.2023.2266926Bibliometric analysis of monoclonal antibodies for atherosclerosisJiqing Ma0Kaiwen Zhao1Yalin Zhu2Wen Xu3Jie Huang4Xiaolong Wei5Zhiqing Zhao6Department of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, ChinaDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, ChinaFaculty of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai, ChinaDepartment of Anesthesiology, Naval Hospital of Eastern Theater, Zhoushan, ChinaFaculty of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai, ChinaDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, ChinaDepartment of Vascular Surgery, Changhai Hospital, Naval Medical University, Shanghai, ChinaAtherosclerosis (AS) is a prevalent cardiovascular disease that greatly increases mortality in the aging population and imposes a heavy burden on global healthcare systems. The purpose of this study is to examine the research structure and current trends of monoclonal antibodies (mAbs) against AS from a bibliometric perspective, since the development of these drugs is currently booming. This study collected articles and reviews on mAbs against AS from the Web of Science Core Collection, spanning from 2003 to 2022. Biblioshiny was utilized to analyze and visualize the characteristics of countries, regions, authors, institutions, and journals included in this collection. We used VOS viewer to illustrate the frequency of country co-occurrence, and CiteSpace to visualize co-cited reference, keywords co-occurrence, keywords citation bursts, keywords clustering and timeline plots. The study included 1325 publications, with the United States emerging as a leading contributor to the field. ATHEROSCLEROSIS, CIRCULATION and ARTERIOSCLEROSISTHROMBOSIS AND VASCULAR BIOLOGY are core journals that publish high-quality literature on the latest advances in the field. Noteworthy authors with numerous high-quality publications include Witztum JL and Tsimikas S. Currently, lipid metabolism and inflammation are the main research areas of interest in this field. The mAbs against AS is an evolving field, and ongoing research continues to advance our understanding. This paper provides a comprehensive overview of the current state of knowledge in this area, highlighting two primary research directions: inflammation and lipid metabolism. Additionally, the paper identifies emerging research hotspots, which will provide researchers with useful insights to guide future investigations and anticipate research directions.https://www.tandfonline.com/doi/10.1080/21645515.2023.2266926Monoclonal antibodiesatherosclerosisbibliometricsmabsCiteSpace
spellingShingle Jiqing Ma
Kaiwen Zhao
Yalin Zhu
Wen Xu
Jie Huang
Xiaolong Wei
Zhiqing Zhao
Bibliometric analysis of monoclonal antibodies for atherosclerosis
Human Vaccines & Immunotherapeutics
Monoclonal antibodies
atherosclerosis
bibliometrics
mabs
CiteSpace
title Bibliometric analysis of monoclonal antibodies for atherosclerosis
title_full Bibliometric analysis of monoclonal antibodies for atherosclerosis
title_fullStr Bibliometric analysis of monoclonal antibodies for atherosclerosis
title_full_unstemmed Bibliometric analysis of monoclonal antibodies for atherosclerosis
title_short Bibliometric analysis of monoclonal antibodies for atherosclerosis
title_sort bibliometric analysis of monoclonal antibodies for atherosclerosis
topic Monoclonal antibodies
atherosclerosis
bibliometrics
mabs
CiteSpace
url https://www.tandfonline.com/doi/10.1080/21645515.2023.2266926
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AT wenxu bibliometricanalysisofmonoclonalantibodiesforatherosclerosis
AT jiehuang bibliometricanalysisofmonoclonalantibodiesforatherosclerosis
AT xiaolongwei bibliometricanalysisofmonoclonalantibodiesforatherosclerosis
AT zhiqingzhao bibliometricanalysisofmonoclonalantibodiesforatherosclerosis