Targeted CRISPR screens reveal genes essential for Cryptosporidium survival in the host intestine

Targeted CRISPR screens reveal genes essential for Cryptosporidium survival in the host intestine

Abstract The Cryptosporidium parasite is one of the leading causes of diarrheal morbidity and mortality in children, and adolescent infections are associated with chronic malnutrition. There are no vaccines available for protection and only one drug approved for treatment that has limited efficacy....

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Main Authors: Lucy C. Watson, Katarzyna A. Sala, Netanya Bernitz, Lotta Baumgärtel, Mitchell A. Pallett, N. Bishara Marzook, Lorian Cobra Straker, Duo Peng, Lucy Collinson, Adam Sateriale
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-63012-1
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