Shared pathogenic mechanisms linking obesity and idiopathic pulmonary fibrosis revealed by bioinformatics and in vivo validation

Shared pathogenic mechanisms linking obesity and idiopathic pulmonary fibrosis revealed by bioinformatics and in vivo validation

Abstract Previous studies have suggested a potential correlation between obesity and idiopathic pulmonary fibrosis (IPF). This study aimed to elucidate pathogenic pathways connecting obesity and IPF and identify diagnostic biomarkers for obesity-related pulmonary fibrosis. Obesity and IPF datasets w...

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Bibliographic Details
Main Authors: Linjie Chen, Haojie Chen, Zinan Chen, Kunyi Zhang, Hongsen Zhang, Jiahe Xu, Tongsheng Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Obesity
Idiopathic pulmonary fibrosis
Bioinformatic analysis
Machine learning
Flavonoids
Online Access:https://doi.org/10.1038/s41598-025-12046-y
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