Opioid analgesics: Managing the predictable
It is imperative for clinicians to understand the common adverse effects of opioid therapy and ensure patients are properly counselled on them prior to opioid initiation. Predictable adverse effects are wide ranging, and include bowel dysfunction, nausea, sedation, endocrinopathy and pruritis. Many...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Clinical Medicine |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S147021182500048X |
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| author | A Barnes G Heppenstall-Harris A Dickman |
| author_facet | A Barnes G Heppenstall-Harris A Dickman |
| author_sort | A Barnes |
| collection | DOAJ |
| description | It is imperative for clinicians to understand the common adverse effects of opioid therapy and ensure patients are properly counselled on them prior to opioid initiation. Predictable adverse effects are wide ranging, and include bowel dysfunction, nausea, sedation, endocrinopathy and pruritis. Many adverse effects (with the notable exception of constipation) improve with time; however, patients should undergo regular re-assessment to identify new or evolving symptoms. Opioid rotation can also be a useful therapeutic tool to mitigate intolerable opioid adverse effects. This article aims to provide a succinct review of important adverse effects and effective management techniques to enhance patient outcomes and quality of life. |
| format | Article |
| id | doaj-art-fd58acae52634c038e9515b82e89809f |
| institution | Kabale University |
| issn | 1470-2118 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Medicine |
| spelling | doaj-art-fd58acae52634c038e9515b82e89809f2025-08-20T03:59:37ZengElsevierClinical Medicine1470-21182025-07-0125410033010.1016/j.clinme.2025.100330Opioid analgesics: Managing the predictableA Barnes0G Heppenstall-Harris1A Dickman2Woodlands Hospice, Liverpool University Hospital Foundation Trust (LUHFT), Liverpool, UK; Corresponding author.Liverpool University Hospital Foundation Trust (LUHFT), Liverpool, UKSpecialist Palliative Care Services, Liverpool University Hospital Foundation Trust (LUHFT), Liverpool, UKIt is imperative for clinicians to understand the common adverse effects of opioid therapy and ensure patients are properly counselled on them prior to opioid initiation. Predictable adverse effects are wide ranging, and include bowel dysfunction, nausea, sedation, endocrinopathy and pruritis. Many adverse effects (with the notable exception of constipation) improve with time; however, patients should undergo regular re-assessment to identify new or evolving symptoms. Opioid rotation can also be a useful therapeutic tool to mitigate intolerable opioid adverse effects. This article aims to provide a succinct review of important adverse effects and effective management techniques to enhance patient outcomes and quality of life.http://www.sciencedirect.com/science/article/pii/S147021182500048XOpioidsAnalgesiaMorphineNauseaConstipationSedation |
| spellingShingle | A Barnes G Heppenstall-Harris A Dickman Opioid analgesics: Managing the predictable Clinical Medicine Opioids Analgesia Morphine Nausea Constipation Sedation |
| title | Opioid analgesics: Managing the predictable |
| title_full | Opioid analgesics: Managing the predictable |
| title_fullStr | Opioid analgesics: Managing the predictable |
| title_full_unstemmed | Opioid analgesics: Managing the predictable |
| title_short | Opioid analgesics: Managing the predictable |
| title_sort | opioid analgesics managing the predictable |
| topic | Opioids Analgesia Morphine Nausea Constipation Sedation |
| url | http://www.sciencedirect.com/science/article/pii/S147021182500048X |
| work_keys_str_mv | AT abarnes opioidanalgesicsmanagingthepredictable AT gheppenstallharris opioidanalgesicsmanagingthepredictable AT adickman opioidanalgesicsmanagingthepredictable |