A Review of the Epidemiology of Lassa Fever in Nigeria

Lassa fever, a viral hemorrhagic illness that first came into the limelight as a clinical entity in 1969 when it was discovered in Northern Nigeria, is now found in other West African countries such as Sierra Leone, Liberia, Guinea, Togo, and the Benin Republic. Over the years, the disease, which is...

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Main Authors: Danny Asogun, Bosede Arogundade, Faith Unuabonah, Olorunkemi Olugbenro, Joyce Asogun, Fatelyn Aluede, Deborah Ehichioya
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/6/1419
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author Danny Asogun
Bosede Arogundade
Faith Unuabonah
Olorunkemi Olugbenro
Joyce Asogun
Fatelyn Aluede
Deborah Ehichioya
author_facet Danny Asogun
Bosede Arogundade
Faith Unuabonah
Olorunkemi Olugbenro
Joyce Asogun
Fatelyn Aluede
Deborah Ehichioya
author_sort Danny Asogun
collection DOAJ
description Lassa fever, a viral hemorrhagic illness that first came into the limelight as a clinical entity in 1969 when it was discovered in Northern Nigeria, is now found in other West African countries such as Sierra Leone, Liberia, Guinea, Togo, and the Benin Republic. Over the years, the disease, which is primarily transmitted from contact with infected mastomys rodents to humans, has the capability of secondary human-to-human transmission with significant morbidity and mortality, especially in healthcare settings. The disease is typically characterized by seasonal outbreaks, which peak during the dry season months of December to March. Lassa fever significantly impacts public health and the socioeconomic life of people in affected communities. In Nigeria, the Integrated Disease Surveillance and Response Strategy (IDSR), along with other medical countermeasures, have been employed to curtail the impact of the disease in endemic regions of Nigeria and other West Africa countries. The one-health approach to combat the disease is a promising strategy. This, along with the hope of a safe and effective vaccine, is a ray of hope on the horizon for public health authorities in Nigeria and other West African countries that the battle against Lassa fever might indeed end sooner than later.
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series Microorganisms
spelling doaj-art-fd5694fda06d451aa7c7737ddfa393c32025-08-20T02:21:11ZengMDPI AGMicroorganisms2076-26072025-06-01136141910.3390/microorganisms13061419A Review of the Epidemiology of Lassa Fever in NigeriaDanny Asogun0Bosede Arogundade1Faith Unuabonah2Olorunkemi Olugbenro3Joyce Asogun4Fatelyn Aluede5Deborah Ehichioya6Institute of Viral and Emergent Pathogens, Irrua Specialist Teaching Hospital, Ekpoma 310115, Edo State, NigeriaDepartment of Planning, Research & Statistics, Federal Ministry of Health, Abuja 900211, FCT, NigeriaInstitute of Viral and Emergent Pathogens, Irrua Specialist Teaching Hospital, Ekpoma 310115, Edo State, NigeriaInstitute of Viral and Emergent Pathogens, Irrua Specialist Teaching Hospital, Ekpoma 310115, Edo State, NigeriaInstitute of Viral and Emergent Pathogens, Irrua Specialist Teaching Hospital, Ekpoma 310115, Edo State, NigeriaInstitute of Viral and Emergent Pathogens, Irrua Specialist Teaching Hospital, Ekpoma 310115, Edo State, NigeriaInstitute of Viral and Emergent Pathogens, Irrua Specialist Teaching Hospital, Ekpoma 310115, Edo State, NigeriaLassa fever, a viral hemorrhagic illness that first came into the limelight as a clinical entity in 1969 when it was discovered in Northern Nigeria, is now found in other West African countries such as Sierra Leone, Liberia, Guinea, Togo, and the Benin Republic. Over the years, the disease, which is primarily transmitted from contact with infected mastomys rodents to humans, has the capability of secondary human-to-human transmission with significant morbidity and mortality, especially in healthcare settings. The disease is typically characterized by seasonal outbreaks, which peak during the dry season months of December to March. Lassa fever significantly impacts public health and the socioeconomic life of people in affected communities. In Nigeria, the Integrated Disease Surveillance and Response Strategy (IDSR), along with other medical countermeasures, have been employed to curtail the impact of the disease in endemic regions of Nigeria and other West Africa countries. The one-health approach to combat the disease is a promising strategy. This, along with the hope of a safe and effective vaccine, is a ray of hope on the horizon for public health authorities in Nigeria and other West African countries that the battle against Lassa fever might indeed end sooner than later.https://www.mdpi.com/2076-2607/13/6/1419Lassa fever virusepidemiologyoutbreakssurveillanceresponse
spellingShingle Danny Asogun
Bosede Arogundade
Faith Unuabonah
Olorunkemi Olugbenro
Joyce Asogun
Fatelyn Aluede
Deborah Ehichioya
A Review of the Epidemiology of Lassa Fever in Nigeria
Microorganisms
Lassa fever virus
epidemiology
outbreaks
surveillance
response
title A Review of the Epidemiology of Lassa Fever in Nigeria
title_full A Review of the Epidemiology of Lassa Fever in Nigeria
title_fullStr A Review of the Epidemiology of Lassa Fever in Nigeria
title_full_unstemmed A Review of the Epidemiology of Lassa Fever in Nigeria
title_short A Review of the Epidemiology of Lassa Fever in Nigeria
title_sort review of the epidemiology of lassa fever in nigeria
topic Lassa fever virus
epidemiology
outbreaks
surveillance
response
url https://www.mdpi.com/2076-2607/13/6/1419
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