L-lysine potentiates aminoglycosides against Acinetobacter baumannii via regulation of proton motive force and antibiotics uptake

L-lysine potentiates aminoglycosides against Acinetobacter baumannii via regulation of proton motive force and antibiotics uptake

Acinetobacter baumannii, a Gram-negative opportunistic pathogen, is a leading cause of hospital- and community-acquired infections. Acinetobacter baumannii can rapidly acquire diverse resistance mechanisms and undergo genetic modifications that confer resistance and persistence to all currently used...

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Bibliographic Details
Main Authors: Wanyan Deng, Tiwei Fu, Zhen Zhang, Xiao Jiang, Jianping Xie, Hang Sun, Peng Hu, Hong Ren, Peifu Zhou, Qi Liu, Quanxin Long
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
Subjects:
L-Lysine
aminoglycosides
Acinetobacter baumannii
proton motive force
reactive oxygen species
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1740611
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