Identification of high-risk COVID-19 patients using machine learning.

The current COVID-19 public health crisis, caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has produced a devastating toll both in terms of human life loss and economic disruption. In this paper we present a machine-learning algorithm capable of identifying whether a given pa...

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Main Authors: Mario A Quiroz-Juárez, Armando Torres-Gómez, Irma Hoyo-Ulloa, Roberto de J León-Montiel, Alfred B U'Ren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0257234
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author Mario A Quiroz-Juárez
Armando Torres-Gómez
Irma Hoyo-Ulloa
Roberto de J León-Montiel
Alfred B U'Ren
author_facet Mario A Quiroz-Juárez
Armando Torres-Gómez
Irma Hoyo-Ulloa
Roberto de J León-Montiel
Alfred B U'Ren
author_sort Mario A Quiroz-Juárez
collection DOAJ
description The current COVID-19 public health crisis, caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has produced a devastating toll both in terms of human life loss and economic disruption. In this paper we present a machine-learning algorithm capable of identifying whether a given patient (actually infected or suspected to be infected) is more likely to survive than to die, or vice-versa. We train this algorithm with historical data, including medical history, demographic data, as well as COVID-19-related information. This is extracted from a database of confirmed and suspected COVID-19 infections in Mexico, constituting the official COVID-19 data compiled and made publicly available by the Mexican Federal Government. We demonstrate that the proposed method can detect high-risk patients with high accuracy, in each of four identified clinical stages, thus improving hospital capacity planning and timely treatment. Furthermore, we show that our method can be extended to provide optimal estimators for hypothesis-testing techniques commonly-used in biological and medical statistics. We believe that our work could be of use in the context of the current pandemic in assisting medical professionals with real-time assessments so as to determine health care priorities.
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spelling doaj-art-fd53ba1150e94166a960b3f5ad9d69da2025-08-20T02:00:56ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01169e025723410.1371/journal.pone.0257234Identification of high-risk COVID-19 patients using machine learning.Mario A Quiroz-JuárezArmando Torres-GómezIrma Hoyo-UlloaRoberto de J León-MontielAlfred B U'RenThe current COVID-19 public health crisis, caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has produced a devastating toll both in terms of human life loss and economic disruption. In this paper we present a machine-learning algorithm capable of identifying whether a given patient (actually infected or suspected to be infected) is more likely to survive than to die, or vice-versa. We train this algorithm with historical data, including medical history, demographic data, as well as COVID-19-related information. This is extracted from a database of confirmed and suspected COVID-19 infections in Mexico, constituting the official COVID-19 data compiled and made publicly available by the Mexican Federal Government. We demonstrate that the proposed method can detect high-risk patients with high accuracy, in each of four identified clinical stages, thus improving hospital capacity planning and timely treatment. Furthermore, we show that our method can be extended to provide optimal estimators for hypothesis-testing techniques commonly-used in biological and medical statistics. We believe that our work could be of use in the context of the current pandemic in assisting medical professionals with real-time assessments so as to determine health care priorities.https://doi.org/10.1371/journal.pone.0257234
spellingShingle Mario A Quiroz-Juárez
Armando Torres-Gómez
Irma Hoyo-Ulloa
Roberto de J León-Montiel
Alfred B U'Ren
Identification of high-risk COVID-19 patients using machine learning.
PLoS ONE
title Identification of high-risk COVID-19 patients using machine learning.
title_full Identification of high-risk COVID-19 patients using machine learning.
title_fullStr Identification of high-risk COVID-19 patients using machine learning.
title_full_unstemmed Identification of high-risk COVID-19 patients using machine learning.
title_short Identification of high-risk COVID-19 patients using machine learning.
title_sort identification of high risk covid 19 patients using machine learning
url https://doi.org/10.1371/journal.pone.0257234
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AT armandotorresgomez identificationofhighriskcovid19patientsusingmachinelearning
AT irmahoyoulloa identificationofhighriskcovid19patientsusingmachinelearning
AT robertodejleonmontiel identificationofhighriskcovid19patientsusingmachinelearning
AT alfredburen identificationofhighriskcovid19patientsusingmachinelearning