Alterations in the gut microbiome and metabolism with doxorubicin-induced heart failure severity

Alterations in the gut microbiome and metabolism with doxorubicin-induced heart failure severity

ObjectiveThis study aimed to explore the changes in gut microbiota and its metabolites in different pathophysiological stages of doxorubicin (DOX)-induced heart failure (DIHF) and the relationship between gut microbiota and metabolites in various degrees of DIHF.Materials and methodsC57BL/6 J mice w...

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Bibliographic Details
Main Authors:	Qian Wang, Meihua Liu, Tianpei Liu, Long Li, Chenyang Wang, Xiaolin Wang, Shuling Rong, Xuedong Zhou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Series:	Frontiers in Microbiology
Subjects:	doxorubicin heart failure gut microbiota 16S rRNA gene sequencing metabolomics multivariate analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2024.1348403/full
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