Experimental perfusion device for preservation of donor’s liver
OBJECTIVE. The authors aimed to develop complex perfusion medical device in order to successfully maintain viability of donor liver until transplantation. MATERIAL AND METHODS. Experimental perfusion device for normothermic perfusion donor’s liver was developed and tested in the Central Research and...
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| Format: | Article |
| Language: | Russian |
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Pavlov First Saint Petersburg State Medical University
2017-06-01
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| Series: | Вестник хирургии имени И.И. Грекова |
| Subjects: | |
| Online Access: | https://www.vestnik-grekova.ru/jour/article/view/461 |
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| _version_ | 1849240416975585280 |
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| author | S. F. Bagnenko O. N. Reznik A. E. Skvortsov A. V. Lopota N. A. Gryaznov V. V. Kharlamov G. S. Kireeva |
| author_facet | S. F. Bagnenko O. N. Reznik A. E. Skvortsov A. V. Lopota N. A. Gryaznov V. V. Kharlamov G. S. Kireeva |
| author_sort | S. F. Bagnenko |
| collection | DOAJ |
| description | OBJECTIVE. The authors aimed to develop complex perfusion medical device in order to successfully maintain viability of donor liver until transplantation. MATERIAL AND METHODS. Experimental perfusion device for normothermic perfusion donor’s liver was developed and tested in the Central Research and Experimental-design Institute of Robotics and Technical Cybernetics. RESULTS. The pre-clinical tests were performed on porcine liver. It was demonstrated that normothermic machine perfusion could restore liver function after 30 minutes of warm ischemia time and provide normalization of biochemical parameters of organ functioning. |
| format | Article |
| id | doaj-art-fd496c01a44741c885cc1c4a67a013de |
| institution | Kabale University |
| issn | 0042-4625 |
| language | Russian |
| publishDate | 2017-06-01 |
| publisher | Pavlov First Saint Petersburg State Medical University |
| record_format | Article |
| series | Вестник хирургии имени И.И. Грекова |
| spelling | doaj-art-fd496c01a44741c885cc1c4a67a013de2025-08-20T04:00:35ZrusPavlov First Saint Petersburg State Medical UniversityВестник хирургии имени И.И. Грекова0042-46252017-06-011763889210.24884/0042-4625-2017-176-3-88-92460Experimental perfusion device for preservation of donor’s liverS. F. Bagnenko0O. N. Reznik1A. E. Skvortsov2A. V. Lopota3N. A. Gryaznov4V. V. Kharlamov5G. S. Kireeva6I. P.Pavlov First St. Petersburg State Medical UniversityI. P.Pavlov First St. Petersburg State Medical University; I. I. Dzhanelidze St. Petersburg Research Institute of Emergency MedicineI. P.Pavlov First St. Petersburg State Medical UniversityCentral Research and Experimental-design Institute of Robotics and Technical CyberneticsCentral Research and Experimental-design Institute of Robotics and Technical CyberneticsCentral Research and Experimental-design Institute of Robotics and Technical CyberneticsCentral Research and Experimental-design Institute of Robotics and Technical CyberneticsOBJECTIVE. The authors aimed to develop complex perfusion medical device in order to successfully maintain viability of donor liver until transplantation. MATERIAL AND METHODS. Experimental perfusion device for normothermic perfusion donor’s liver was developed and tested in the Central Research and Experimental-design Institute of Robotics and Technical Cybernetics. RESULTS. The pre-clinical tests were performed on porcine liver. It was demonstrated that normothermic machine perfusion could restore liver function after 30 minutes of warm ischemia time and provide normalization of biochemical parameters of organ functioning.https://www.vestnik-grekova.ru/jour/article/view/461liver transplantnormothermic perfusion ex vivoexperimental device |
| spellingShingle | S. F. Bagnenko O. N. Reznik A. E. Skvortsov A. V. Lopota N. A. Gryaznov V. V. Kharlamov G. S. Kireeva Experimental perfusion device for preservation of donor’s liver Вестник хирургии имени И.И. Грекова liver transplant normothermic perfusion ex vivo experimental device |
| title | Experimental perfusion device for preservation of donor’s liver |
| title_full | Experimental perfusion device for preservation of donor’s liver |
| title_fullStr | Experimental perfusion device for preservation of donor’s liver |
| title_full_unstemmed | Experimental perfusion device for preservation of donor’s liver |
| title_short | Experimental perfusion device for preservation of donor’s liver |
| title_sort | experimental perfusion device for preservation of donor s liver |
| topic | liver transplant normothermic perfusion ex vivo experimental device |
| url | https://www.vestnik-grekova.ru/jour/article/view/461 |
| work_keys_str_mv | AT sfbagnenko experimentalperfusiondeviceforpreservationofdonorsliver AT onreznik experimentalperfusiondeviceforpreservationofdonorsliver AT aeskvortsov experimentalperfusiondeviceforpreservationofdonorsliver AT avlopota experimentalperfusiondeviceforpreservationofdonorsliver AT nagryaznov experimentalperfusiondeviceforpreservationofdonorsliver AT vvkharlamov experimentalperfusiondeviceforpreservationofdonorsliver AT gskireeva experimentalperfusiondeviceforpreservationofdonorsliver |