Molecular characterization of ovarian mesonephric-like adenocarcinoma: Insights from single-cell RNA sequencing and mitochondrial metabolism

Molecular characterization of ovarian mesonephric-like adenocarcinoma: Insights from single-cell RNA sequencing and mitochondrial metabolism

Objectives: Ovarian mesonephric-like adenocarcinoma (MLA) is a rare malignancy with limited understanding of its molecular features and therapeutic vulnerabilities. Although similar to uterine MLA, its unique characteristics remain undefined. This study aimed to characterize ovarian MLA using single...

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Bibliographic Details
Main Authors: Gwan Hee Han, Ye-Ah Kim, Hyunjin Park, Hee Yun, Jae-Hoon Kim, Man S. Kim, Hanbyoul Cho
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Gynecologic Oncology Reports
Subjects:
Ovarian mesonephric like adenocarcinoma
Single-cell RNA sequencing
Mitochondrial reprogramming
Therapeutic target
Cellular heterogeneity
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578924003163
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