Laparoscopic appendectomy for metastatic cervical cancer presenting as appendicitis
Abstract Background Metastatic lesions to the appendix are rare. They usually present with acute appendicitis or remain asymptomatic and are diagnosed incidentally. Metastases to the appendix have been reported from a number of primary tumor sites including ovary, colon, gastric and lung. We report...
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Japan Surgical Society
2021-05-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-021-01196-6 |
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| author | Shota Fukai Alan Kawarai Lefor Ken Mizokami |
| author_facet | Shota Fukai Alan Kawarai Lefor Ken Mizokami |
| author_sort | Shota Fukai |
| collection | DOAJ |
| description | Abstract Background Metastatic lesions to the appendix are rare. They usually present with acute appendicitis or remain asymptomatic and are diagnosed incidentally. Metastases to the appendix have been reported from a number of primary tumor sites including ovary, colon, gastric and lung. We report a laparoscopic appendectomy for a metachronous metastatic lesion to the appendix from the uterine cervix. Case presentation A 68-year-old woman, who underwent radical hysterectomy for cervical cancer 16 years previously, presented with nausea and gradually worsening right lower quadrant abdominal pain. Abdominal computed tomography scan showed an enlarged appendix and periappendiceal fat stranding. She was diagnosed with appendicitis and underwent laparoscopic appendectomy. Pathological findings showed adenocarcinoma in the submucosa and muscularis propria. Gastrointestinal endoscopy and positron emission tomography with computed tomography (PET–CT) did not show other lesions. Immunohistochemical analysis showed cytokeratin 7 (CK7) positive, cytokeratin 20 (CK20) negative, estrogen receptor (ER) 70–80% and progesterone receptor (PgR) 40–50%. The ER and PgR expression was similar to the cervical lesion 16 years previously, and the diagnosis was a metastatic lesion to the appendix from the uterine cervix. Conclusions Metastasis to the appendix from cancer of the uterine cervix is a rare lesion. |
| format | Article |
| id | doaj-art-fd42acaabd704dd4954e5b11a94e54fb |
| institution | Kabale University |
| issn | 2198-7793 |
| language | English |
| publishDate | 2021-05-01 |
| publisher | Japan Surgical Society |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj-art-fd42acaabd704dd4954e5b11a94e54fb2025-08-20T03:42:10ZengJapan Surgical SocietySurgical Case Reports2198-77932021-05-01711510.1186/s40792-021-01196-6Laparoscopic appendectomy for metastatic cervical cancer presenting as appendicitisShota Fukai0Alan Kawarai Lefor1Ken Mizokami2Department of Surgery, Tokyo Bay Medical CenterDepartment of Surgery, Jichi Medical UniversityDepartment of Surgery, Tokyo Bay Medical CenterAbstract Background Metastatic lesions to the appendix are rare. They usually present with acute appendicitis or remain asymptomatic and are diagnosed incidentally. Metastases to the appendix have been reported from a number of primary tumor sites including ovary, colon, gastric and lung. We report a laparoscopic appendectomy for a metachronous metastatic lesion to the appendix from the uterine cervix. Case presentation A 68-year-old woman, who underwent radical hysterectomy for cervical cancer 16 years previously, presented with nausea and gradually worsening right lower quadrant abdominal pain. Abdominal computed tomography scan showed an enlarged appendix and periappendiceal fat stranding. She was diagnosed with appendicitis and underwent laparoscopic appendectomy. Pathological findings showed adenocarcinoma in the submucosa and muscularis propria. Gastrointestinal endoscopy and positron emission tomography with computed tomography (PET–CT) did not show other lesions. Immunohistochemical analysis showed cytokeratin 7 (CK7) positive, cytokeratin 20 (CK20) negative, estrogen receptor (ER) 70–80% and progesterone receptor (PgR) 40–50%. The ER and PgR expression was similar to the cervical lesion 16 years previously, and the diagnosis was a metastatic lesion to the appendix from the uterine cervix. Conclusions Metastasis to the appendix from cancer of the uterine cervix is a rare lesion.https://doi.org/10.1186/s40792-021-01196-6Appendiceal neoplasmsMetastasisCervical cancer |
| spellingShingle | Shota Fukai Alan Kawarai Lefor Ken Mizokami Laparoscopic appendectomy for metastatic cervical cancer presenting as appendicitis Surgical Case Reports Appendiceal neoplasms Metastasis Cervical cancer |
| title | Laparoscopic appendectomy for metastatic cervical cancer presenting as appendicitis |
| title_full | Laparoscopic appendectomy for metastatic cervical cancer presenting as appendicitis |
| title_fullStr | Laparoscopic appendectomy for metastatic cervical cancer presenting as appendicitis |
| title_full_unstemmed | Laparoscopic appendectomy for metastatic cervical cancer presenting as appendicitis |
| title_short | Laparoscopic appendectomy for metastatic cervical cancer presenting as appendicitis |
| title_sort | laparoscopic appendectomy for metastatic cervical cancer presenting as appendicitis |
| topic | Appendiceal neoplasms Metastasis Cervical cancer |
| url | https://doi.org/10.1186/s40792-021-01196-6 |
| work_keys_str_mv | AT shotafukai laparoscopicappendectomyformetastaticcervicalcancerpresentingasappendicitis AT alankawarailefor laparoscopicappendectomyformetastaticcervicalcancerpresentingasappendicitis AT kenmizokami laparoscopicappendectomyformetastaticcervicalcancerpresentingasappendicitis |