Is it safe to proceed with heart transplant in a patient with active tuberculosis? Strategies and challenges based on a case report
Transplant candidates are at increased risk of developing active tuberculosis (TB), and its diagnosis and treatment may be especially challenging. Although screening and treatment for TB are recommended in heart transplant candidates, there is lack of evidence on how to manage active TB infection in...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | JHLT Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S295013342400137X |
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| author | Laura Hastenteufel Marcelo Basso Gazzana Nadine Clausell Lívia Adams Goldraich, MD |
| author_facet | Laura Hastenteufel Marcelo Basso Gazzana Nadine Clausell Lívia Adams Goldraich, MD |
| author_sort | Laura Hastenteufel |
| collection | DOAJ |
| description | Transplant candidates are at increased risk of developing active tuberculosis (TB), and its diagnosis and treatment may be especially challenging. Although screening and treatment for TB are recommended in heart transplant candidates, there is lack of evidence on how to manage active TB infection in this scenario. Herein, we report challenges of performing a heart transplant in a 69-year-old patient with progressive heart failure and active, symptomatic TB infection. We aimed to emphasize the importance of proper screening of TB in solid organ transplant candidates, as well as to suggest that, in selected patients, it may be safe to proceed with transplant after an initial period of treatment with antituberculous agents. |
| format | Article |
| id | doaj-art-fd380bcc03d54a2491dc613fa6c59fed |
| institution | Kabale University |
| issn | 2950-1334 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JHLT Open |
| spelling | doaj-art-fd380bcc03d54a2491dc613fa6c59fed2025-02-09T05:01:58ZengElsevierJHLT Open2950-13342025-02-017100188Is it safe to proceed with heart transplant in a patient with active tuberculosis? Strategies and challenges based on a case reportLaura Hastenteufel0Marcelo Basso Gazzana1Nadine Clausell2Lívia Adams Goldraich, MD3Heart Transplant Program, Division of Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, BrazilDivision of Pneumology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, BrazilHeart Transplant Program, Division of Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, BrazilHeart Transplant Program, Division of Cardiology, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil; Corresponding author: Lívia Adams Goldraich, Heart Transplant Program - Division of Cardiology, Hospital de Clínicas de Porto Alegre, Rua Ramiro Barcelos, 2350 - Building C, room 301, Porto Alegre, RS 90035–003, Brazil.Transplant candidates are at increased risk of developing active tuberculosis (TB), and its diagnosis and treatment may be especially challenging. Although screening and treatment for TB are recommended in heart transplant candidates, there is lack of evidence on how to manage active TB infection in this scenario. Herein, we report challenges of performing a heart transplant in a 69-year-old patient with progressive heart failure and active, symptomatic TB infection. We aimed to emphasize the importance of proper screening of TB in solid organ transplant candidates, as well as to suggest that, in selected patients, it may be safe to proceed with transplant after an initial period of treatment with antituberculous agents.http://www.sciencedirect.com/science/article/pii/S295013342400137XHeart transplantActive tuberculosis |
| spellingShingle | Laura Hastenteufel Marcelo Basso Gazzana Nadine Clausell Lívia Adams Goldraich, MD Is it safe to proceed with heart transplant in a patient with active tuberculosis? Strategies and challenges based on a case report JHLT Open Heart transplant Active tuberculosis |
| title | Is it safe to proceed with heart transplant in a patient with active tuberculosis? Strategies and challenges based on a case report |
| title_full | Is it safe to proceed with heart transplant in a patient with active tuberculosis? Strategies and challenges based on a case report |
| title_fullStr | Is it safe to proceed with heart transplant in a patient with active tuberculosis? Strategies and challenges based on a case report |
| title_full_unstemmed | Is it safe to proceed with heart transplant in a patient with active tuberculosis? Strategies and challenges based on a case report |
| title_short | Is it safe to proceed with heart transplant in a patient with active tuberculosis? Strategies and challenges based on a case report |
| title_sort | is it safe to proceed with heart transplant in a patient with active tuberculosis strategies and challenges based on a case report |
| topic | Heart transplant Active tuberculosis |
| url | http://www.sciencedirect.com/science/article/pii/S295013342400137X |
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