Bayesian hierarchical model predicts biopharmaceutical stability indicators and shelf life with application to multivalent human papillomavirus vaccine
Abstract Predictive stability is demonstrated as a powerful method for assessing the shelf-life of biopharmaceutical products, such as therapeutic proteins and vaccines. A Bayesian hierarchical multi-level stability model is illustrated for the Human Papillomavirus (HPV) 9-valent recombinant sub-uni...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-99458-y |
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