New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based Solutions

Across communities worldwide, various new psychoactive substances (NPSs) continue to emerge, which worsens the challenges to global mental health, drug rules, and public health risks, as well as combats their usage. Specifically, the vast number of NPSs that are currently available, coupled with the...

Full description

Saved in:
Bibliographic Details
Main Authors: Chinaza Godswill Awuchi, Maduabuchi Patrick Aja, Nancy Bonareri Mitaki, Sonia Morya, Ikechukwu O. Amagwula, Chinelo Kate Echeta, Victory S. Igwe
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2023/5852315
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849468466758680576
author Chinaza Godswill Awuchi
Maduabuchi Patrick Aja
Nancy Bonareri Mitaki
Sonia Morya
Ikechukwu O. Amagwula
Chinelo Kate Echeta
Victory S. Igwe
author_facet Chinaza Godswill Awuchi
Maduabuchi Patrick Aja
Nancy Bonareri Mitaki
Sonia Morya
Ikechukwu O. Amagwula
Chinelo Kate Echeta
Victory S. Igwe
author_sort Chinaza Godswill Awuchi
collection DOAJ
description Across communities worldwide, various new psychoactive substances (NPSs) continue to emerge, which worsens the challenges to global mental health, drug rules, and public health risks, as well as combats their usage. Specifically, the vast number of NPSs that are currently available, coupled with the rate at which new ones emerge worldwide, increasingly challenges both forensic and clinical testing strategies. The well-established NPS detection techniques include immunoassays, colorimetric tests, mass spectrometric techniques, chromatographic techniques, and hyphenated types. Nonetheless, mitigating drug abuse and NPS usage is achievable through extensive community-based initiatives, with increased focus on harm reduction. Clinically validated and reliable testing of NPS from human samples, along with community-driven solution, such as harm reduction, will be of great importance, especially in combating their prevalence and the use of other illicit synthetic substances. There is a need for continued literature synthesis to reiterate the importance of NPS, given the continuous emergence of illicit substances in the recent years. All these are discussed in this overview, as we performed another look into NPS, from differentiating the major groups and identifying with laboratory testing challenges to community-based initiatives.
format Article
id doaj-art-fd2a9549e05d4c869a78943d35accc6a
institution Kabale University
issn 2090-9071
language English
publishDate 2023-01-01
publisher Wiley
record_format Article
series Journal of Chemistry
spelling doaj-art-fd2a9549e05d4c869a78943d35accc6a2025-08-20T03:25:50ZengWileyJournal of Chemistry2090-90712023-01-01202310.1155/2023/5852315New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based SolutionsChinaza Godswill Awuchi0Maduabuchi Patrick Aja1Nancy Bonareri Mitaki2Sonia Morya3Ikechukwu O. Amagwula4Chinelo Kate Echeta5Victory S. Igwe6School of Natural and Applied SciencesDepartment of BiochemistryDepartment of Biochemistry3444Across communities worldwide, various new psychoactive substances (NPSs) continue to emerge, which worsens the challenges to global mental health, drug rules, and public health risks, as well as combats their usage. Specifically, the vast number of NPSs that are currently available, coupled with the rate at which new ones emerge worldwide, increasingly challenges both forensic and clinical testing strategies. The well-established NPS detection techniques include immunoassays, colorimetric tests, mass spectrometric techniques, chromatographic techniques, and hyphenated types. Nonetheless, mitigating drug abuse and NPS usage is achievable through extensive community-based initiatives, with increased focus on harm reduction. Clinically validated and reliable testing of NPS from human samples, along with community-driven solution, such as harm reduction, will be of great importance, especially in combating their prevalence and the use of other illicit synthetic substances. There is a need for continued literature synthesis to reiterate the importance of NPS, given the continuous emergence of illicit substances in the recent years. All these are discussed in this overview, as we performed another look into NPS, from differentiating the major groups and identifying with laboratory testing challenges to community-based initiatives.http://dx.doi.org/10.1155/2023/5852315
spellingShingle Chinaza Godswill Awuchi
Maduabuchi Patrick Aja
Nancy Bonareri Mitaki
Sonia Morya
Ikechukwu O. Amagwula
Chinelo Kate Echeta
Victory S. Igwe
New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based Solutions
Journal of Chemistry
title New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based Solutions
title_full New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based Solutions
title_fullStr New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based Solutions
title_full_unstemmed New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based Solutions
title_short New Psychoactive Substances: Major Groups, Laboratory Testing Challenges, Public Health Concerns, and Community-Based Solutions
title_sort new psychoactive substances major groups laboratory testing challenges public health concerns and community based solutions
url http://dx.doi.org/10.1155/2023/5852315
work_keys_str_mv AT chinazagodswillawuchi newpsychoactivesubstancesmajorgroupslaboratorytestingchallengespublichealthconcernsandcommunitybasedsolutions
AT maduabuchipatrickaja newpsychoactivesubstancesmajorgroupslaboratorytestingchallengespublichealthconcernsandcommunitybasedsolutions
AT nancybonarerimitaki newpsychoactivesubstancesmajorgroupslaboratorytestingchallengespublichealthconcernsandcommunitybasedsolutions
AT soniamorya newpsychoactivesubstancesmajorgroupslaboratorytestingchallengespublichealthconcernsandcommunitybasedsolutions
AT ikechukwuoamagwula newpsychoactivesubstancesmajorgroupslaboratorytestingchallengespublichealthconcernsandcommunitybasedsolutions
AT chinelokateecheta newpsychoactivesubstancesmajorgroupslaboratorytestingchallengespublichealthconcernsandcommunitybasedsolutions
AT victorysigwe newpsychoactivesubstancesmajorgroupslaboratorytestingchallengespublichealthconcernsandcommunitybasedsolutions