Health Benefits of Ganoderma lucidum as a Medicinal Mushroom
Ganoderma lucidum (Curtis) P. Karst., known as “Lingzhi” in China or “Reishi” in Japan, is a well-known medicinal mushroom and traditional Chinese medicine, which has been used for the prevention and treatment of bronchitis, allergies, hepatitis, immunological disorders and cancer. G. lucidum is rar...
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Hasan Eleroğlu
2019-12-01
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| Series: | Turkish Journal of Agriculture: Food Science and Technology |
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| Online Access: | http://www.agrifoodscience.com/index.php/TURJAF/article/view/2728 |
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| author | Sanem Bulam Nebahat Şule Üstün Aysun Pekşen |
| author_facet | Sanem Bulam Nebahat Şule Üstün Aysun Pekşen |
| author_sort | Sanem Bulam |
| collection | DOAJ |
| description | Ganoderma lucidum (Curtis) P. Karst., known as “Lingzhi” in China or “Reishi” in Japan, is a well-known medicinal mushroom and traditional Chinese medicine, which has been used for the prevention and treatment of bronchitis, allergies, hepatitis, immunological disorders and cancer. G. lucidum is rarely collected from nature and mostly cultivated on wood logs and sawdust in plastic bags or bottles to meet the demands of international markets. Diverse groups of chemical compounds with pharmacological activities, isolated from the mycelia and fruiting bodies of G. lucidum are triterpenoids, polysaccharides (β-D-glucans), proteins, amino acids, nucleosides, alkaloids, steroids, lactones, lectins, fatty acids, and enzymes. The biologically active compounds as primarily triterpenoids and polysaccharides of G. lucidum have been reported to possess hepatoprotective, antihypertensive, hypocholesterolemic, antihistaminic effects and antioxidant, antitumor, immunomodulatory, and antiangiogenic activities. Several formulations have been developed, patented and used as nutraceuticals, nutriceuticals and pharmaceuticals from G. lucidum’s water or ethanol extracts and rarely purified active compounds. As the result of clinical trials, various products have commercially become available as syrup, injection, tablet, tincture or bolus of powdered medicine and an ingredient or additive in dark chocolate bars and organic fermented medicinal mushroom drink mixes such as green teas, coffees, and hot cacaos. This review has intended to give and discuss recent knowledge on phytochemical and pharmacological compositions, therapeutic and side effects, clinical trials, and commercial products of G. lucidum. |
| format | Article |
| id | doaj-art-fd25d608be994742a1ac0e3cf0afabab |
| institution | OA Journals |
| issn | 2148-127X |
| language | English |
| publishDate | 2019-12-01 |
| publisher | Hasan Eleroğlu |
| record_format | Article |
| series | Turkish Journal of Agriculture: Food Science and Technology |
| spelling | doaj-art-fd25d608be994742a1ac0e3cf0afabab2025-08-20T02:05:02ZengHasan EleroğluTurkish Journal of Agriculture: Food Science and Technology2148-127X2019-12-017sp1849310.24925/turjaf.v7isp1.84-93.27281350Health Benefits of Ganoderma lucidum as a Medicinal MushroomSanem Bulam0Nebahat Şule Üstün1Aysun Pekşen2Department of Food Engineering, Faculty of Engineering, Giresun University, Güre Campus, 28200 GiresunDepartment of Food Engineering, Faculty of Engineering, Ondokuz Mayıs University, Kurupelit Campus, 55139 Atakum/SamsunDepartment of Horticulture, Faculty of Agriculture, Ondokuz Mayıs University, Kurupelit Campus, 55139 Atakum/SamsunGanoderma lucidum (Curtis) P. Karst., known as “Lingzhi” in China or “Reishi” in Japan, is a well-known medicinal mushroom and traditional Chinese medicine, which has been used for the prevention and treatment of bronchitis, allergies, hepatitis, immunological disorders and cancer. G. lucidum is rarely collected from nature and mostly cultivated on wood logs and sawdust in plastic bags or bottles to meet the demands of international markets. Diverse groups of chemical compounds with pharmacological activities, isolated from the mycelia and fruiting bodies of G. lucidum are triterpenoids, polysaccharides (β-D-glucans), proteins, amino acids, nucleosides, alkaloids, steroids, lactones, lectins, fatty acids, and enzymes. The biologically active compounds as primarily triterpenoids and polysaccharides of G. lucidum have been reported to possess hepatoprotective, antihypertensive, hypocholesterolemic, antihistaminic effects and antioxidant, antitumor, immunomodulatory, and antiangiogenic activities. Several formulations have been developed, patented and used as nutraceuticals, nutriceuticals and pharmaceuticals from G. lucidum’s water or ethanol extracts and rarely purified active compounds. As the result of clinical trials, various products have commercially become available as syrup, injection, tablet, tincture or bolus of powdered medicine and an ingredient or additive in dark chocolate bars and organic fermented medicinal mushroom drink mixes such as green teas, coffees, and hot cacaos. This review has intended to give and discuss recent knowledge on phytochemical and pharmacological compositions, therapeutic and side effects, clinical trials, and commercial products of G. lucidum.http://www.agrifoodscience.com/index.php/TURJAF/article/view/2728clinical trialsganoderma lucidummedicinalpharmacological |
| spellingShingle | Sanem Bulam Nebahat Şule Üstün Aysun Pekşen Health Benefits of Ganoderma lucidum as a Medicinal Mushroom Turkish Journal of Agriculture: Food Science and Technology clinical trials ganoderma lucidum medicinal pharmacological |
| title | Health Benefits of Ganoderma lucidum as a Medicinal Mushroom |
| title_full | Health Benefits of Ganoderma lucidum as a Medicinal Mushroom |
| title_fullStr | Health Benefits of Ganoderma lucidum as a Medicinal Mushroom |
| title_full_unstemmed | Health Benefits of Ganoderma lucidum as a Medicinal Mushroom |
| title_short | Health Benefits of Ganoderma lucidum as a Medicinal Mushroom |
| title_sort | health benefits of ganoderma lucidum as a medicinal mushroom |
| topic | clinical trials ganoderma lucidum medicinal pharmacological |
| url | http://www.agrifoodscience.com/index.php/TURJAF/article/view/2728 |
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