Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer Survivors
Objective. Breast cancer survivors are highly sedentary, overweight, or obese, which puts them at increased risk for comorbid chronic disease. We examined the prevalence of, and changes in, metabolic syndrome following 6 months of an aerobic exercise versus usual care intervention in a sample of sed...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/168797 |
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| _version_ | 1849469608150433792 |
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| author | Gwendolyn A. Thomas Marty Alvarez-Reeves Lingeng Lu Herbert Yu Melinda L. Irwin |
| author_facet | Gwendolyn A. Thomas Marty Alvarez-Reeves Lingeng Lu Herbert Yu Melinda L. Irwin |
| author_sort | Gwendolyn A. Thomas |
| collection | DOAJ |
| description | Objective. Breast cancer survivors are highly sedentary, overweight, or obese, which puts them at increased risk for comorbid chronic disease. We examined the prevalence of, and changes in, metabolic syndrome following 6 months of an aerobic exercise versus usual care intervention in a sample of sedentary postmenopausal breast cancer survivors. Design and Methods. 65 participants were randomized to an aerobic exercise intervention (EX) (n=35) mean BMI 30.8 (±5.9) kg/m2 or usual care (UC) (n=30) mean BMI 29.4 (±7.4) kg/m2. Metabolic syndrome prevalence was determined, as well as change in criteria and overall metabolic syndrome. Results. At baseline, 55.4% of total women met the criteria for metabolic syndrome. There was no statistically significant change in metabolic syndrome when comparing EX and UC. However, adhering to the exercise intervention (at least 120 mins/week of exercise) resulted in a significant (P=.009) decrease in metabolic syndrome z-score from baseline to 6 months (-0.76±0.36) when compared to those who did not adhere (0.80±0.42). Conclusions. Due to a higher prevalence of metabolic syndrome in breast cancer survivors, lifestyle interventions are needed to prevent chronic diseases associated with obesity. Increasing exercise adherence is a necessary target for further research in obese breast cancer survivors. |
| format | Article |
| id | doaj-art-fd22acf3a1fa45b1ba40023cb9f26650 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-fd22acf3a1fa45b1ba40023cb9f266502025-08-20T03:25:26ZengWileyInternational Journal of Endocrinology1687-83371687-83452013-01-01201310.1155/2013/168797168797Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer SurvivorsGwendolyn A. Thomas0Marty Alvarez-Reeves1Lingeng Lu2Herbert Yu3Melinda L. Irwin4Yale University, New Haven, CT, USADana Farber Cancer Institute, Boston, MA, USAYale School of Public Health, New Haven, CT, USAUniversity of Hawaii Cancer Center, Honolulu, HI, USAYale School of Public Health, New Haven, CT, USAObjective. Breast cancer survivors are highly sedentary, overweight, or obese, which puts them at increased risk for comorbid chronic disease. We examined the prevalence of, and changes in, metabolic syndrome following 6 months of an aerobic exercise versus usual care intervention in a sample of sedentary postmenopausal breast cancer survivors. Design and Methods. 65 participants were randomized to an aerobic exercise intervention (EX) (n=35) mean BMI 30.8 (±5.9) kg/m2 or usual care (UC) (n=30) mean BMI 29.4 (±7.4) kg/m2. Metabolic syndrome prevalence was determined, as well as change in criteria and overall metabolic syndrome. Results. At baseline, 55.4% of total women met the criteria for metabolic syndrome. There was no statistically significant change in metabolic syndrome when comparing EX and UC. However, adhering to the exercise intervention (at least 120 mins/week of exercise) resulted in a significant (P=.009) decrease in metabolic syndrome z-score from baseline to 6 months (-0.76±0.36) when compared to those who did not adhere (0.80±0.42). Conclusions. Due to a higher prevalence of metabolic syndrome in breast cancer survivors, lifestyle interventions are needed to prevent chronic diseases associated with obesity. Increasing exercise adherence is a necessary target for further research in obese breast cancer survivors.http://dx.doi.org/10.1155/2013/168797 |
| spellingShingle | Gwendolyn A. Thomas Marty Alvarez-Reeves Lingeng Lu Herbert Yu Melinda L. Irwin Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer Survivors International Journal of Endocrinology |
| title | Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer Survivors |
| title_full | Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer Survivors |
| title_fullStr | Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer Survivors |
| title_full_unstemmed | Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer Survivors |
| title_short | Effect of Exercise on Metabolic Syndrome Variables in Breast Cancer Survivors |
| title_sort | effect of exercise on metabolic syndrome variables in breast cancer survivors |
| url | http://dx.doi.org/10.1155/2013/168797 |
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