Mycobacterium leprae Slide Positivity at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: Seven Years Retrospective Study
ABSTRACT Background Mycobacterium leprae is the cause of leprosy, a disease whose severity worsens over time. It affects the nerves of the extremities, the integumentary systems, the linings of appendages like the nose, and the upper respiratory tract. This study aimed to determine the of M. leprae...
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Wiley
2025-04-01
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| Series: | Health Science Reports |
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| Online Access: | https://doi.org/10.1002/hsr2.70737 |
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| author | Mulat Erkihun Ayenew Assefa Biruk Legese Andargachew Almaw Ayenew Berhan Birhanu Getie Teklehaimanot Kiros Alemie Fentie Yenealem Solomon Bekele Sharew Zelalem Asmare Bayu Ayele |
| author_facet | Mulat Erkihun Ayenew Assefa Biruk Legese Andargachew Almaw Ayenew Berhan Birhanu Getie Teklehaimanot Kiros Alemie Fentie Yenealem Solomon Bekele Sharew Zelalem Asmare Bayu Ayele |
| author_sort | Mulat Erkihun |
| collection | DOAJ |
| description | ABSTRACT Background Mycobacterium leprae is the cause of leprosy, a disease whose severity worsens over time. It affects the nerves of the extremities, the integumentary systems, the linings of appendages like the nose, and the upper respiratory tract. This study aimed to determine the of M. leprae slide positivity in Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia. Method Patients’ record from January 2017 to December 2023 was reviewed and extracted from laboratory registration book. Socio‐demographic data like age, sex, and confirmed cases were collected carefully. Data were cleaned, coded, entered and analyzed with statistical package for social sciences version 23. Result The prevalence of M. leprae was 21.8% (138/633). Among M. leprae skin slit acid‐fast positive‐registered cases, 91.3% (126/138) were males and 8.7% (12/138) were females. The majority of M. leprae slide positive cases (78.3%, 108/138) were detected from patients in the age range of 15–46 years old. Based on this study finding, male sex is significantly associated with M. leprae slide positivity (AOR = 6 [1.8–15.4], 95% CI, p = 0.001). Conclusion The prevalence of M. leprae slide acid‐fast bacilli positivity is relatively high. The high prevalence of M. leprae slide positivity, particularly among males, underscores the importance of targeted case detection strategies in this demographic to control leprosy. This study indicated that acid‐fast bacilli positivity of M. leprae is higher in males than females. |
| format | Article |
| id | doaj-art-fd1d6900ae524119ac81da3617f37a23 |
| institution | DOAJ |
| issn | 2398-8835 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Health Science Reports |
| spelling | doaj-art-fd1d6900ae524119ac81da3617f37a232025-08-20T03:11:58ZengWileyHealth Science Reports2398-88352025-04-0184n/an/a10.1002/hsr2.70737Mycobacterium leprae Slide Positivity at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: Seven Years Retrospective StudyMulat Erkihun0Ayenew Assefa1Biruk Legese2Andargachew Almaw3Ayenew Berhan4Birhanu Getie5Teklehaimanot Kiros6Alemie Fentie7Yenealem Solomon8Bekele Sharew9Zelalem Asmare10Bayu Ayele11Department of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Health Sciences, Debre Tabor University Debre Tabor EthiopiaDepartment of Medical Laboratory Sciences College of Medicine and Health Sciences, Injibara University Injibara EthiopiaLaboratory Service Unit Felege Hiwot Comprehensive Specialized Hospital Bahir Dar EthiopiaABSTRACT Background Mycobacterium leprae is the cause of leprosy, a disease whose severity worsens over time. It affects the nerves of the extremities, the integumentary systems, the linings of appendages like the nose, and the upper respiratory tract. This study aimed to determine the of M. leprae slide positivity in Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia. Method Patients’ record from January 2017 to December 2023 was reviewed and extracted from laboratory registration book. Socio‐demographic data like age, sex, and confirmed cases were collected carefully. Data were cleaned, coded, entered and analyzed with statistical package for social sciences version 23. Result The prevalence of M. leprae was 21.8% (138/633). Among M. leprae skin slit acid‐fast positive‐registered cases, 91.3% (126/138) were males and 8.7% (12/138) were females. The majority of M. leprae slide positive cases (78.3%, 108/138) were detected from patients in the age range of 15–46 years old. Based on this study finding, male sex is significantly associated with M. leprae slide positivity (AOR = 6 [1.8–15.4], 95% CI, p = 0.001). Conclusion The prevalence of M. leprae slide acid‐fast bacilli positivity is relatively high. The high prevalence of M. leprae slide positivity, particularly among males, underscores the importance of targeted case detection strategies in this demographic to control leprosy. This study indicated that acid‐fast bacilli positivity of M. leprae is higher in males than females.https://doi.org/10.1002/hsr2.70737acid fast bacillileprosyMycobacterium leprae |
| spellingShingle | Mulat Erkihun Ayenew Assefa Biruk Legese Andargachew Almaw Ayenew Berhan Birhanu Getie Teklehaimanot Kiros Alemie Fentie Yenealem Solomon Bekele Sharew Zelalem Asmare Bayu Ayele Mycobacterium leprae Slide Positivity at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: Seven Years Retrospective Study Health Science Reports acid fast bacilli leprosy Mycobacterium leprae |
| title | Mycobacterium leprae Slide Positivity at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: Seven Years Retrospective Study |
| title_full | Mycobacterium leprae Slide Positivity at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: Seven Years Retrospective Study |
| title_fullStr | Mycobacterium leprae Slide Positivity at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: Seven Years Retrospective Study |
| title_full_unstemmed | Mycobacterium leprae Slide Positivity at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: Seven Years Retrospective Study |
| title_short | Mycobacterium leprae Slide Positivity at Felege Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia: Seven Years Retrospective Study |
| title_sort | mycobacterium leprae slide positivity at felege hiwot comprehensive specialized hospital northwest ethiopia seven years retrospective study |
| topic | acid fast bacilli leprosy Mycobacterium leprae |
| url | https://doi.org/10.1002/hsr2.70737 |
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