Congenital syphilis: a rare presentation of a forgotten infection
Congenital syphilis (CS), a common but forgotten disease has a broad spectrum of clinical presentation. Vertical transmission of this spirochaetal infection from the pregnant mother to the foetus can result in varied manifestations ranging from asymptomatic infection to life- threatening conditions...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2023-01-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/15498 |
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| author | Anusha Hegde Ranjini Srinivasan Chitra Dinakar |
| author_facet | Anusha Hegde Ranjini Srinivasan Chitra Dinakar |
| author_sort | Anusha Hegde |
| collection | DOAJ |
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Congenital syphilis (CS), a common but forgotten disease has a broad spectrum of clinical presentation. Vertical transmission of this spirochaetal infection from the pregnant mother to the foetus can result in varied manifestations ranging from asymptomatic infection to life- threatening conditions in the form of stillbirth and neonatal death. The haematological and visceral manifestations of this disease can closely mimic various conditions including haemolytic anaemia and malignancies. Congenital syphilis should be considered as a differential in any infant presenting with hepatosplenomegaly and haematological abnormalities even if the antenatal screen was negative. We report a 6-month-old infant with congenital syphilis presenting with organomegaly, bicytopenia and monocytosis. A strong index of suspicion and early diagnosis is the key to the good outcome as treatment is simple and cost- effective.
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| format | Article |
| id | doaj-art-fd1d227a8aa843ba8b35dec13b9cd670 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-fd1d227a8aa843ba8b35dec13b9cd6702025-08-20T02:16:14ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802023-01-01170110.3855/jidc.15498Congenital syphilis: a rare presentation of a forgotten infectionAnusha Hegde0Ranjini Srinivasan1Chitra Dinakar2Department of Pediatrics, St. Johns Medical College Hospital, Johnnagar, Bengaluru, Karnataka, IndiaDepartment of Pediatrics, St. Johns Medical College Hospital, Johnnagar, Bengaluru, Karnataka, IndiaDepartment of Pediatrics, St. Johns Medical College Hospital, Johnnagar, Bengaluru, Karnataka, India Congenital syphilis (CS), a common but forgotten disease has a broad spectrum of clinical presentation. Vertical transmission of this spirochaetal infection from the pregnant mother to the foetus can result in varied manifestations ranging from asymptomatic infection to life- threatening conditions in the form of stillbirth and neonatal death. The haematological and visceral manifestations of this disease can closely mimic various conditions including haemolytic anaemia and malignancies. Congenital syphilis should be considered as a differential in any infant presenting with hepatosplenomegaly and haematological abnormalities even if the antenatal screen was negative. We report a 6-month-old infant with congenital syphilis presenting with organomegaly, bicytopenia and monocytosis. A strong index of suspicion and early diagnosis is the key to the good outcome as treatment is simple and cost- effective. https://jidc.org/index.php/journal/article/view/15498Congenital syphilismonocytosisanemiathrombocytopenia |
| spellingShingle | Anusha Hegde Ranjini Srinivasan Chitra Dinakar Congenital syphilis: a rare presentation of a forgotten infection Journal of Infection in Developing Countries Congenital syphilis monocytosis anemia thrombocytopenia |
| title | Congenital syphilis: a rare presentation of a forgotten infection |
| title_full | Congenital syphilis: a rare presentation of a forgotten infection |
| title_fullStr | Congenital syphilis: a rare presentation of a forgotten infection |
| title_full_unstemmed | Congenital syphilis: a rare presentation of a forgotten infection |
| title_short | Congenital syphilis: a rare presentation of a forgotten infection |
| title_sort | congenital syphilis a rare presentation of a forgotten infection |
| topic | Congenital syphilis monocytosis anemia thrombocytopenia |
| url | https://jidc.org/index.php/journal/article/view/15498 |
| work_keys_str_mv | AT anushahegde congenitalsyphilisararepresentationofaforgotteninfection AT ranjinisrinivasan congenitalsyphilisararepresentationofaforgotteninfection AT chitradinakar congenitalsyphilisararepresentationofaforgotteninfection |