Detecting Demyelination by PET: The Lesion as Imaging Target
Noninvasive imaging of demyelination and remyelination is critical for diagnosis and clinical management of demyelinating diseases. Positron emission tomography (PET) has the potential to complement magnetic resonance imaging (MRI) by providing a quantitative measure specific to demyelination. In Br...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2018-07-01
|
| Series: | Molecular Imaging |
| Online Access: | https://doi.org/10.1177/1536012118785471 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841561897705406464 |
|---|---|
| author | Pedro Brugarolas PhD Daniel S. Reich MD, PhD Brian Popko PhD |
| author_facet | Pedro Brugarolas PhD Daniel S. Reich MD, PhD Brian Popko PhD |
| author_sort | Pedro Brugarolas PhD |
| collection | DOAJ |
| description | Noninvasive imaging of demyelination and remyelination is critical for diagnosis and clinical management of demyelinating diseases. Positron emission tomography (PET) has the potential to complement magnetic resonance imaging (MRI) by providing a quantitative measure specific to demyelination. In Brugarolas et al’s study 1 , we describe the development of the first PET tracer for voltage-gated K + channels based on a clinically approved drug for multiple sclerosis that can be used for imaging demyelination in animal models. |
| format | Article |
| id | doaj-art-fd1cd080e2b2404099938efc8beef81b |
| institution | Kabale University |
| issn | 1536-0121 |
| language | English |
| publishDate | 2018-07-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Molecular Imaging |
| spelling | doaj-art-fd1cd080e2b2404099938efc8beef81b2025-01-03T01:22:46ZengSAGE PublishingMolecular Imaging1536-01212018-07-011710.1177/1536012118785471Detecting Demyelination by PET: The Lesion as Imaging TargetPedro Brugarolas PhD0Daniel S. Reich MD, PhD1Brian Popko PhD2 Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA Department of Neurology, University of Chicago, Chicago, IL, USANoninvasive imaging of demyelination and remyelination is critical for diagnosis and clinical management of demyelinating diseases. Positron emission tomography (PET) has the potential to complement magnetic resonance imaging (MRI) by providing a quantitative measure specific to demyelination. In Brugarolas et al’s study 1 , we describe the development of the first PET tracer for voltage-gated K + channels based on a clinically approved drug for multiple sclerosis that can be used for imaging demyelination in animal models.https://doi.org/10.1177/1536012118785471 |
| spellingShingle | Pedro Brugarolas PhD Daniel S. Reich MD, PhD Brian Popko PhD Detecting Demyelination by PET: The Lesion as Imaging Target Molecular Imaging |
| title | Detecting Demyelination by PET: The Lesion as Imaging Target |
| title_full | Detecting Demyelination by PET: The Lesion as Imaging Target |
| title_fullStr | Detecting Demyelination by PET: The Lesion as Imaging Target |
| title_full_unstemmed | Detecting Demyelination by PET: The Lesion as Imaging Target |
| title_short | Detecting Demyelination by PET: The Lesion as Imaging Target |
| title_sort | detecting demyelination by pet the lesion as imaging target |
| url | https://doi.org/10.1177/1536012118785471 |
| work_keys_str_mv | AT pedrobrugarolasphd detectingdemyelinationbypetthelesionasimagingtarget AT danielsreichmdphd detectingdemyelinationbypetthelesionasimagingtarget AT brianpopkophd detectingdemyelinationbypetthelesionasimagingtarget |