Contribution of CARD9 signaling to wound healing in skin promoted by topical administration of heat-killed Enterococcus faecalis strain KH2 and the involvement of Dectin-2

Contribution of CARD9 signaling to wound healing in skin promoted by topical administration of heat-killed Enterococcus faecalis strain KH2 and the involvement of Dectin-2

IntroductionLactic acid bacteria (LAB) are well known for their beneficial effects on the regulation of immune responses and host protection against microbial infections. We previously reported that heat-killed Enterococcus faecalis strain KH2 (heat-killed KH2), a species of LAB, enhances inflammato...

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Main Authors: Shiho Kurosaka, Hiromasa Tanno, Minako Hirose, Wakana Kamada, Rena Takayashiki, Ikue Sone, Yuki Sato, Takumi Watanabe, Shinyo Ishi, Miki Shoji, Yoshimichi Imai, Ko Sato, Keiko Ishii, Hiromitsu Hara, Sho Yamasaki, Shinobu Saijo, Yoichiro Iwakura, Kazuyoshi Kawakami, Emi Kanno
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
skin wound healing
Enterococcus faecalis KH2
C-type lectin receptors
CARD9
Dectin-2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1550934/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1550934/full

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