Improving diagnostic antimicrobial stewardship in respiratory tract infections: a protocol for a scoping review investigating point-of-care testing programmes in community pharmacy
Introduction Diagnostic uncertainty regarding the cause of respiratory tract infections (RTIs) multiplies the problem of unnecessary use of antibiotics and antimicrobial resistance in primary care. Point-of-care testing (POCT) programmes have been recognised as a potential stewardship strategy to op...
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BMJ Publishing Group
2023-02-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/2/e068193.full |
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| author | Elizabeth Manias Suzanne Robinson Sajal K Saha Nomvuyo Mothobi Shukla Promite Carly L Botheras Eugene Athan |
| author_facet | Elizabeth Manias Suzanne Robinson Sajal K Saha Nomvuyo Mothobi Shukla Promite Carly L Botheras Eugene Athan |
| author_sort | Elizabeth Manias |
| collection | DOAJ |
| description | Introduction Diagnostic uncertainty regarding the cause of respiratory tract infections (RTIs) multiplies the problem of unnecessary use of antibiotics and antimicrobial resistance in primary care. Point-of-care testing (POCT) programmes have been recognised as a potential stewardship strategy to optimise antimicrobial use in primary care. There is a need for greater understanding of community pharmacy-based POCT programmes in reducing the unnecessary use of antimicrobials in patients with RTIs. This review systematically maps out evidence around the effectiveness, feasibility and implementation challenges of POCT programmes in community pharmacy to improve safe antimicrobial use in RTIs.Methods and analysis The Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist and the Arksey and O’Malley methodology framework will guide the reporting of this review. We will systematically review studies with either randomised controlled trial, non-randomised controlled trial, before–after study, observational study or pilot feasibility study design. Medline, Emcare, PubMed, Health Technology Assessment, Cochrane Central Register of Controlled Trials and Google Scholar databases will be used to search for articles. Three reviewers will independently screen, review and select studies with POCT programmes involving community pharmacists for antimicrobial stewardship in RTIs. Summary statistics and random effects model, if data permit, will be used to summarise the effectiveness, feasibility and cost-effectiveness of the POCT programme. The Consolidated Framework for Implementation Research will capture POCT implementation drivers.Ethics and dissemination This review study does not require research ethics approval. Findings will be disseminated through national and international conferences, seminars and publication in a peer-reviewed journal. |
| format | Article |
| id | doaj-art-fd0d7301fbb04288a5c098819837b149 |
| institution | DOAJ |
| issn | 2044-6055 |
| language | English |
| publishDate | 2023-02-01 |
| publisher | BMJ Publishing Group |
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| series | BMJ Open |
| spelling | doaj-art-fd0d7301fbb04288a5c098819837b1492025-08-20T03:01:22ZengBMJ Publishing GroupBMJ Open2044-60552023-02-0113210.1136/bmjopen-2022-068193Improving diagnostic antimicrobial stewardship in respiratory tract infections: a protocol for a scoping review investigating point-of-care testing programmes in community pharmacyElizabeth Manias0Suzanne Robinson1Sajal K Saha2Nomvuyo Mothobi3Shukla Promite4Carly L Botheras5Eugene Athan6Quality and Safety Patient Research Centre, Deakin University, Geelong, Victoria, AustraliaDeakin Health Economics, Institute for Health Transformation, Deakin University, Geelong, Victoria, AustraliaSchool of Medicine, Deakin University, Geelong, Victoria, AustraliaCentre for Innovation in Infectious Disease and Immunology Research (CIIDIR), Barwon Health, Geelong, Victoria, AustraliaSchool of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, AustraliaCentre for Innovation in Infectious Disease and Immunology Research (CIIDIR), Barwon Health, Geelong, Victoria, AustraliaSchool of Medicine, Deakin University, Geelong, Victoria, AustraliaIntroduction Diagnostic uncertainty regarding the cause of respiratory tract infections (RTIs) multiplies the problem of unnecessary use of antibiotics and antimicrobial resistance in primary care. Point-of-care testing (POCT) programmes have been recognised as a potential stewardship strategy to optimise antimicrobial use in primary care. There is a need for greater understanding of community pharmacy-based POCT programmes in reducing the unnecessary use of antimicrobials in patients with RTIs. This review systematically maps out evidence around the effectiveness, feasibility and implementation challenges of POCT programmes in community pharmacy to improve safe antimicrobial use in RTIs.Methods and analysis The Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist and the Arksey and O’Malley methodology framework will guide the reporting of this review. We will systematically review studies with either randomised controlled trial, non-randomised controlled trial, before–after study, observational study or pilot feasibility study design. Medline, Emcare, PubMed, Health Technology Assessment, Cochrane Central Register of Controlled Trials and Google Scholar databases will be used to search for articles. Three reviewers will independently screen, review and select studies with POCT programmes involving community pharmacists for antimicrobial stewardship in RTIs. Summary statistics and random effects model, if data permit, will be used to summarise the effectiveness, feasibility and cost-effectiveness of the POCT programme. The Consolidated Framework for Implementation Research will capture POCT implementation drivers.Ethics and dissemination This review study does not require research ethics approval. Findings will be disseminated through national and international conferences, seminars and publication in a peer-reviewed journal.https://bmjopen.bmj.com/content/13/2/e068193.full |
| spellingShingle | Elizabeth Manias Suzanne Robinson Sajal K Saha Nomvuyo Mothobi Shukla Promite Carly L Botheras Eugene Athan Improving diagnostic antimicrobial stewardship in respiratory tract infections: a protocol for a scoping review investigating point-of-care testing programmes in community pharmacy BMJ Open |
| title | Improving diagnostic antimicrobial stewardship in respiratory tract infections: a protocol for a scoping review investigating point-of-care testing programmes in community pharmacy |
| title_full | Improving diagnostic antimicrobial stewardship in respiratory tract infections: a protocol for a scoping review investigating point-of-care testing programmes in community pharmacy |
| title_fullStr | Improving diagnostic antimicrobial stewardship in respiratory tract infections: a protocol for a scoping review investigating point-of-care testing programmes in community pharmacy |
| title_full_unstemmed | Improving diagnostic antimicrobial stewardship in respiratory tract infections: a protocol for a scoping review investigating point-of-care testing programmes in community pharmacy |
| title_short | Improving diagnostic antimicrobial stewardship in respiratory tract infections: a protocol for a scoping review investigating point-of-care testing programmes in community pharmacy |
| title_sort | improving diagnostic antimicrobial stewardship in respiratory tract infections a protocol for a scoping review investigating point of care testing programmes in community pharmacy |
| url | https://bmjopen.bmj.com/content/13/2/e068193.full |
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