Percutaneous Transcatheter Closure of Post-infarction Ventricular Septal Defect: An Alternative to Surgical Intervention

Post-infarction ventricular septal defect is a mechanical complication of acute MI. The incidence of this complication is low in the primary percutaneous coronary intervention era. However, the associated mortality is very high at 94% with medical management alone. Open surgical repair or percutaneo...

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Main Authors: Diarmaid Cadogan, Marwa Daghem, Mostafa Snosi, Lynne K Williams, Jonathan Weir-McCall, Patrick A Calvert, Joel P Giblett
Format: Article
Language:English
Published: Radcliffe Medical Media 2023-05-01
Series:Interventional Cardiology: Reviews, Research, Resources
Online Access:https://www.icrjournal.com/articleindex/icr.2023.01
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author Diarmaid Cadogan
Marwa Daghem
Mostafa Snosi
Lynne K Williams
Jonathan Weir-McCall
Patrick A Calvert
Joel P Giblett
author_facet Diarmaid Cadogan
Marwa Daghem
Mostafa Snosi
Lynne K Williams
Jonathan Weir-McCall
Patrick A Calvert
Joel P Giblett
author_sort Diarmaid Cadogan
collection DOAJ
description Post-infarction ventricular septal defect is a mechanical complication of acute MI. The incidence of this complication is low in the primary percutaneous coronary intervention era. However, the associated mortality is very high at 94% with medical management alone. Open surgical repair or percutaneous transcatheter closure still has an in-hospital mortality >40%. Retrospective comparisons between both closure methods are limited by observation and selection bias. This review addresses the assessment and optimisation of patients prior to repair, the optimal timing of repair, and the limitations in current data. The review considers techniques for percutaneous closure, and finally considers the path that future research should take to improve outcomes for patients.
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issn 1756-1477
1756-1485
language English
publishDate 2023-05-01
publisher Radcliffe Medical Media
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series Interventional Cardiology: Reviews, Research, Resources
spelling doaj-art-fd096c83107e4477bdb9a450d40a12f12025-08-20T01:56:35ZengRadcliffe Medical MediaInterventional Cardiology: Reviews, Research, Resources1756-14771756-14852023-05-011810.15420/icr.2023.01Percutaneous Transcatheter Closure of Post-infarction Ventricular Septal Defect: An Alternative to Surgical InterventionDiarmaid Cadogan0Marwa Daghem1Mostafa Snosi2Lynne K Williams3Jonathan Weir-McCall4Patrick A Calvert5Joel P Giblett6Department of Cardiology, Liverpool Heart and Chest Hospital, Liverpool, UKDepartment of Cardiology, Liverpool Heart and Chest Hospital, Liverpool, UKDepartment of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, UKDepartment of Cardiology, Royal Papworth Hospital, Cambridge, UKDepartment of Radiology, Royal Papworth Hospital, Cambridge, UK; Division of Cardiovascular Medicine, University of Cambridge, Cambridge, UKDepartment of Cardiology, Royal Papworth Hospital, Cambridge, UK; Division of Cardiovascular Medicine, University of Cambridge, Cambridge, UKDepartment of Cardiology, Liverpool Heart and Chest Hospital, Liverpool, UK; Liverpool Centre for Cardiovascular Science, University of Liverpool, Liverpool, UKPost-infarction ventricular septal defect is a mechanical complication of acute MI. The incidence of this complication is low in the primary percutaneous coronary intervention era. However, the associated mortality is very high at 94% with medical management alone. Open surgical repair or percutaneous transcatheter closure still has an in-hospital mortality >40%. Retrospective comparisons between both closure methods are limited by observation and selection bias. This review addresses the assessment and optimisation of patients prior to repair, the optimal timing of repair, and the limitations in current data. The review considers techniques for percutaneous closure, and finally considers the path that future research should take to improve outcomes for patients.https://www.icrjournal.com/articleindex/icr.2023.01
spellingShingle Diarmaid Cadogan
Marwa Daghem
Mostafa Snosi
Lynne K Williams
Jonathan Weir-McCall
Patrick A Calvert
Joel P Giblett
Percutaneous Transcatheter Closure of Post-infarction Ventricular Septal Defect: An Alternative to Surgical Intervention
Interventional Cardiology: Reviews, Research, Resources
title Percutaneous Transcatheter Closure of Post-infarction Ventricular Septal Defect: An Alternative to Surgical Intervention
title_full Percutaneous Transcatheter Closure of Post-infarction Ventricular Septal Defect: An Alternative to Surgical Intervention
title_fullStr Percutaneous Transcatheter Closure of Post-infarction Ventricular Septal Defect: An Alternative to Surgical Intervention
title_full_unstemmed Percutaneous Transcatheter Closure of Post-infarction Ventricular Septal Defect: An Alternative to Surgical Intervention
title_short Percutaneous Transcatheter Closure of Post-infarction Ventricular Septal Defect: An Alternative to Surgical Intervention
title_sort percutaneous transcatheter closure of post infarction ventricular septal defect an alternative to surgical intervention
url https://www.icrjournal.com/articleindex/icr.2023.01
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