Sickle cell disease and Bartonella spp. infection

<p>Sickle cell disease is the most common hereditary hematologic disorder in the world. Painful vaso-occlusive crises are the hallmark of the disease and it is difficult to treat. Chronic infection is related to a higher painful crisis rate in these patients. <em>Bartonel...

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Bibliographic Details
Main Authors: Paulo Eduardo Neves Ferreira Velho, Marna Elise Ericson, David Mair, Kalpna Gupta
Format: Article
Language:English
Published: PAGEPress Publications 2012-01-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
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Online Access:http://www.mjhid.org/article/view/10496
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Summary:<p>Sickle cell disease is the most common hereditary hematologic disorder in the world. Painful vaso-occlusive crises are the hallmark of the disease and it is difficult to treat. Chronic infection is related to a higher painful crisis rate in these patients. <em>Bartonella</em> spp. are fastidious bacteria of zoonotic transmission. They can cause human asymptomatic infection as well as fatal outcome. Pain, fatigue and fever, characteristic features of <em>Bartonella</em> spp. infection are manifest in sickle cell disease patients. <em>Bartonella</em> spp. infection should be ruled in sickle cell disease patients.</p>
ISSN:2035-3006