HapNetworkView: a tool for haplotype network exploration and visualization

Abstract Background Haplotype networks are useful for investigating the genealogical relationships among haplotypes and have been extensively used in molecular evolution and population genetic studies. However, existing tools for visualizing haplotype networks lack comprehensive functionalities for...

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Main Authors: Lianjiang Chi, Yi Dong, Ruizhen Wang, Suiyuan Yang, Lan Wu, Yongbiao Xue, Hua Chen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-025-11206-8
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author Lianjiang Chi
Yi Dong
Ruizhen Wang
Suiyuan Yang
Lan Wu
Yongbiao Xue
Hua Chen
author_facet Lianjiang Chi
Yi Dong
Ruizhen Wang
Suiyuan Yang
Lan Wu
Yongbiao Xue
Hua Chen
author_sort Lianjiang Chi
collection DOAJ
description Abstract Background Haplotype networks are useful for investigating the genealogical relationships among haplotypes and have been extensively used in molecular evolution and population genetic studies. However, existing tools for visualizing haplotype networks lack comprehensive functionalities for data exploration and layout adjustments. Therefore, there is a need for a useful tool capable of constructing and visualizing haplotype networks, facilitating the exploration of data, particularly with datasets with large sample sizes. Results We present HapNetworkView, a user-friendly tool that facilitates the construction and interactive visualization of haplotype networks, enabling users to explore haplotypes and mutation information effectively. HapNetworkView offers both automatic optimization and manual adjustment for haplotype network layouts. Additionally, HapNetworkView supports various input and output formats, as well as color customization. Conclusions These comprehensive functionalities collectively satisfy various needs of users in haplotype network analysis, making HapNetworkView a valuable tool.
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institution Kabale University
issn 1471-2164
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publishDate 2025-01-01
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series BMC Genomics
spelling doaj-art-fce8545830d749bf85f98781cbf4640e2025-01-26T12:16:36ZengBMCBMC Genomics1471-21642025-01-012611610.1186/s12864-025-11206-8HapNetworkView: a tool for haplotype network exploration and visualizationLianjiang Chi0Yi Dong1Ruizhen Wang2Suiyuan Yang3Lan Wu4Yongbiao Xue5Hua Chen6Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for BioinformationBeijing Institute of Genomics, Chinese Academy of Sciences and China National Center for BioinformationBeijing Institute of Genomics, Chinese Academy of Sciences and China National Center for BioinformationBeijing Institute of Genomics, Chinese Academy of Sciences and China National Center for BioinformationBeijing Institute of Genomics, Chinese Academy of Sciences and China National Center for BioinformationBeijing Institute of Genomics, Chinese Academy of Sciences and China National Center for BioinformationBeijing Institute of Genomics, Chinese Academy of Sciences and China National Center for BioinformationAbstract Background Haplotype networks are useful for investigating the genealogical relationships among haplotypes and have been extensively used in molecular evolution and population genetic studies. However, existing tools for visualizing haplotype networks lack comprehensive functionalities for data exploration and layout adjustments. Therefore, there is a need for a useful tool capable of constructing and visualizing haplotype networks, facilitating the exploration of data, particularly with datasets with large sample sizes. Results We present HapNetworkView, a user-friendly tool that facilitates the construction and interactive visualization of haplotype networks, enabling users to explore haplotypes and mutation information effectively. HapNetworkView offers both automatic optimization and manual adjustment for haplotype network layouts. Additionally, HapNetworkView supports various input and output formats, as well as color customization. Conclusions These comprehensive functionalities collectively satisfy various needs of users in haplotype network analysis, making HapNetworkView a valuable tool.https://doi.org/10.1186/s12864-025-11206-8Haplotype networkVisualizationExplorationPopulation genetics
spellingShingle Lianjiang Chi
Yi Dong
Ruizhen Wang
Suiyuan Yang
Lan Wu
Yongbiao Xue
Hua Chen
HapNetworkView: a tool for haplotype network exploration and visualization
BMC Genomics
Haplotype network
Visualization
Exploration
Population genetics
title HapNetworkView: a tool for haplotype network exploration and visualization
title_full HapNetworkView: a tool for haplotype network exploration and visualization
title_fullStr HapNetworkView: a tool for haplotype network exploration and visualization
title_full_unstemmed HapNetworkView: a tool for haplotype network exploration and visualization
title_short HapNetworkView: a tool for haplotype network exploration and visualization
title_sort hapnetworkview a tool for haplotype network exploration and visualization
topic Haplotype network
Visualization
Exploration
Population genetics
url https://doi.org/10.1186/s12864-025-11206-8
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