Effect of high flux hemodialysis on hyperhomocysteinemia and left ventricular structure in maintenance hemodialysis patients
Objective To investigate the effects of high flux hemodialysis(HFHD) on hyperhomocysteinemia and left ventricular structure in maintenance hemodialysis(MHD) patients.Methods A prospective and grouping control study was conducted.From November 2014 to November 2015,a total of 45 hemodialysis patients...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2017-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57918364&Fpath=home&index=0 |
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| Summary: | Objective To investigate the effects of high flux hemodialysis(HFHD) on hyperhomocysteinemia and left ventricular structure in maintenance hemodialysis(MHD) patients.Methods A prospective and grouping control study was conducted.From November 2014 to November 2015,a total of 45 hemodialysis patients with hyperhomocysteinemia were selected,and divided into the HFHD group(n = 23) and the low flux dialysis(LFHD) group(n = 22).Hcy was determined before and6 months after treatment At the same time,the left ventricular structure and function were estimated by color Doppler ultrasonic instrument,and the side effects were recorded.Results After the treatment,Hcy level was reduced from(24.63 ± 7.21) μmol/L to(12.06 ± 5.24) μmol/L in HFHD group,and that from(26.01 ± 8.17) μmol/L to(16.15 ± 6.21) μmol/L in LFHD group.There was significant difference between the two groups(P<0.05).There were significant differences between two groups in the root diameter of pulmonary artery,left ventricular and diastolic diameter,anterior and posterior diameter of left atrium,right ventricular anterior and posterior diameter,left ventricular mass index(LVMI) and left ventricular ejection fraction(LVEF)(P<0.05),but there was no significant difference in IVST between two groups(P>0.05).No serious adverse events were observed.Conclusions HFHD can clear Hcy effectively,and improve the left ventricular structure in MHD patients.It’s worthy of popularization and applicatioa |
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| ISSN: | 1671-2390 |