Handgrip strength measurement protocols in individuals with Down syndrome: a systematic review and meta-regression<subtitle>Handgrip strength measurement protocols and Down syndrome</subtitle>
Background Handgrip strength (HGS) serves as a robust predictor of overall strength across various populations, including individuals with Down Syndrome (DS).Objective To analyze the HGS measurement protocols used in studies involving individuals with DS.Methods Primary sources were sourced from six...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Annals of Medicine |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/07853890.2025.2453077 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832584971446910976 |
|---|---|
| author | Geiziane L. R. Melo Rafaela C. Espírito Santo Viney P. Dubey Cesar Agostinis-Sobrinho |
| author_facet | Geiziane L. R. Melo Rafaela C. Espírito Santo Viney P. Dubey Cesar Agostinis-Sobrinho |
| author_sort | Geiziane L. R. Melo |
| collection | DOAJ |
| description | Background Handgrip strength (HGS) serves as a robust predictor of overall strength across various populations, including individuals with Down Syndrome (DS).Objective To analyze the HGS measurement protocols used in studies involving individuals with DS.Methods Primary sources were sourced from six databases: PubMed, Scopus, Ovid, Embase, ERIC, and Web of Science, spanning from inception to 23rd December 2023. Inclusion criteria focused on individuals with DS, compared with control groups, and examined HGS measurement protocols and outcomes. Meta-regression was utilized to assess bias associated with HGS values concerning different measurement protocols.Results Out of 29 studies involving 1816 participants, most controlled for body position (65%), arm position (82%), elbow position (82%), wrist position (62%), handgrip duration (55%), hand adjustment to dynamometer (62%), verbal encouragement (75%), and familiarization (44.8%). The number of reported variables in the HGS protocol was significantly associated with an increase in HGS, with a mean estimate of 20.59 units (SE = 2.59, p < 0.0001, 95% CI [15.49–25.68]), though there was notable heterogeneity (I2 = 94.33%). The spline regression analysis showed that the model explained 82.66% of the variation in HGS, with adults having 47.61 units higher HGS than children (p = 0.0009), while obesity was linked to a decrease of 15.68 units (p = 0.0675). Sample size and group had no significant effects.Conclusion Overall, protocols for assessing HGS in DS studies are comprehensive yet heterogeneous. Higher HGS values correlated with adherence to standard protocols. |
| format | Article |
| id | doaj-art-fce4df783d5f45e9bf89e070b452fc3f |
| institution | Kabale University |
| issn | 0785-3890 1365-2060 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Medicine |
| spelling | doaj-art-fce4df783d5f45e9bf89e070b452fc3f2025-01-27T08:04:23ZengTaylor & Francis GroupAnnals of Medicine0785-38901365-20602025-12-0157110.1080/07853890.2025.2453077Handgrip strength measurement protocols in individuals with Down syndrome: a systematic review and meta-regression<subtitle>Handgrip strength measurement protocols and Down syndrome</subtitle>Geiziane L. R. Melo0Rafaela C. Espírito Santo1Viney P. Dubey2Cesar Agostinis-Sobrinho3Health Research and Innovatioin Science Centre, Klaipeda University, Klaipeda, LithuaniaHealth Research and Innovatioin Science Centre, Klaipeda University, Klaipeda, LithuaniaHealth Research and Innovatioin Science Centre, Klaipeda University, Klaipeda, LithuaniaHealth Research and Innovatioin Science Centre, Klaipeda University, Klaipeda, LithuaniaBackground Handgrip strength (HGS) serves as a robust predictor of overall strength across various populations, including individuals with Down Syndrome (DS).Objective To analyze the HGS measurement protocols used in studies involving individuals with DS.Methods Primary sources were sourced from six databases: PubMed, Scopus, Ovid, Embase, ERIC, and Web of Science, spanning from inception to 23rd December 2023. Inclusion criteria focused on individuals with DS, compared with control groups, and examined HGS measurement protocols and outcomes. Meta-regression was utilized to assess bias associated with HGS values concerning different measurement protocols.Results Out of 29 studies involving 1816 participants, most controlled for body position (65%), arm position (82%), elbow position (82%), wrist position (62%), handgrip duration (55%), hand adjustment to dynamometer (62%), verbal encouragement (75%), and familiarization (44.8%). The number of reported variables in the HGS protocol was significantly associated with an increase in HGS, with a mean estimate of 20.59 units (SE = 2.59, p < 0.0001, 95% CI [15.49–25.68]), though there was notable heterogeneity (I2 = 94.33%). The spline regression analysis showed that the model explained 82.66% of the variation in HGS, with adults having 47.61 units higher HGS than children (p = 0.0009), while obesity was linked to a decrease of 15.68 units (p = 0.0675). Sample size and group had no significant effects.Conclusion Overall, protocols for assessing HGS in DS studies are comprehensive yet heterogeneous. Higher HGS values correlated with adherence to standard protocols.https://www.tandfonline.com/doi/10.1080/07853890.2025.2453077Intellectual disabilitymuscle strength dynamometerrisk assessmenttrisomy 21muscle strength |
| spellingShingle | Geiziane L. R. Melo Rafaela C. Espírito Santo Viney P. Dubey Cesar Agostinis-Sobrinho Handgrip strength measurement protocols in individuals with Down syndrome: a systematic review and meta-regression<subtitle>Handgrip strength measurement protocols and Down syndrome</subtitle> Annals of Medicine Intellectual disability muscle strength dynamometer risk assessment trisomy 21 muscle strength |
| title | Handgrip strength measurement protocols in individuals with Down syndrome: a systematic review and meta-regression<subtitle>Handgrip strength measurement protocols and Down syndrome</subtitle> |
| title_full | Handgrip strength measurement protocols in individuals with Down syndrome: a systematic review and meta-regression<subtitle>Handgrip strength measurement protocols and Down syndrome</subtitle> |
| title_fullStr | Handgrip strength measurement protocols in individuals with Down syndrome: a systematic review and meta-regression<subtitle>Handgrip strength measurement protocols and Down syndrome</subtitle> |
| title_full_unstemmed | Handgrip strength measurement protocols in individuals with Down syndrome: a systematic review and meta-regression<subtitle>Handgrip strength measurement protocols and Down syndrome</subtitle> |
| title_short | Handgrip strength measurement protocols in individuals with Down syndrome: a systematic review and meta-regression<subtitle>Handgrip strength measurement protocols and Down syndrome</subtitle> |
| title_sort | handgrip strength measurement protocols in individuals with down syndrome a systematic review and meta regression subtitle handgrip strength measurement protocols and down syndrome subtitle |
| topic | Intellectual disability muscle strength dynamometer risk assessment trisomy 21 muscle strength |
| url | https://www.tandfonline.com/doi/10.1080/07853890.2025.2453077 |
| work_keys_str_mv | AT geizianelrmelo handgripstrengthmeasurementprotocolsinindividualswithdownsyndromeasystematicreviewandmetaregressionsubtitlehandgripstrengthmeasurementprotocolsanddownsyndromesubtitle AT rafaelacespiritosanto handgripstrengthmeasurementprotocolsinindividualswithdownsyndromeasystematicreviewandmetaregressionsubtitlehandgripstrengthmeasurementprotocolsanddownsyndromesubtitle AT vineypdubey handgripstrengthmeasurementprotocolsinindividualswithdownsyndromeasystematicreviewandmetaregressionsubtitlehandgripstrengthmeasurementprotocolsanddownsyndromesubtitle AT cesaragostinissobrinho handgripstrengthmeasurementprotocolsinindividualswithdownsyndromeasystematicreviewandmetaregressionsubtitlehandgripstrengthmeasurementprotocolsanddownsyndromesubtitle |