Zwilch kinetochore protein affects the prognosis of cancer patients by participating in cell proliferation, enhancing cell communication, and reshaping the tumor microenvironment

Zwilch kinetochore protein affects the prognosis of cancer patients by participating in cell proliferation, enhancing cell communication, and reshaping the tumor microenvironment

Abstract Background Zwilch Kinetochore Protein(ZWILCH) has been reported to prevent cells from prematurely exiting mitosis. However, the underlying mechanisms or involvement of ZWILCH in the tumor immune microenvironment in various cancers remain largely unknown. Methods Generalized dysregulation of...

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Bibliographic Details
Main Authors: Long Yao, Lianpo Liu, Jinsong Wu, Yunlong Huang, Renquan Zhang, Haoxue Zhang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
ZWILCH
Cancer
TME
Single-cell
Spatial transcriptome
Online Access:https://doi.org/10.1007/s12672-025-02981-7
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