Application of targeted next-generation sequencing for pathogens diagnosis and drug resistance prediction in bronchoalveolar lavage fluid of pulmonary infections

Application of targeted next-generation sequencing for pathogens diagnosis and drug resistance prediction in bronchoalveolar lavage fluid of pulmonary infections

BackgroundRecently, targeted next-generation sequencing (tNGS) have been extensively utilized for the identification of pathogens in pulmonary infections, there have been some studies systematically evaluating differences in the efficacy of tNGS and conventional microbiological tests (CMTs) in bronc...

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Bibliographic Details
Main Authors: Qiugui Xu, Qiumei Chen, Wen Qiu, Lili Liu, Wan Zeng, Jinling Chen, Yangyang Li, Zhen Guo, Ling Rong, Bigui Chen, Jinxiu Yao, Liye Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
targeted next-generation sequencing (TNGS)
conventional microbiological tests (CMTs)
pulmonary infection
bronchoalveolar lavage fluid (BALF)
pathogens
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1590881/full
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