Case Report: Late simultaneous metastasis of renal clear cell carcinoma to the ampulla and breast
We present the case of a 67-year-old female who developed simultaneous metastases to the ampulla of Vater and the breast. Her medical history is significant for a radical nephrectomy performed twenty-one years prior for renal cell carcinoma (RCC). The patient was referred for evaluation due to the d...
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| Language: | English |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1604170/full |
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| author | Guofeng Dai Shuya Li Lei Sun Gangpu Wang |
| author_facet | Guofeng Dai Shuya Li Lei Sun Gangpu Wang |
| author_sort | Guofeng Dai |
| collection | DOAJ |
| description | We present the case of a 67-year-old female who developed simultaneous metastases to the ampulla of Vater and the breast. Her medical history is significant for a radical nephrectomy performed twenty-one years prior for renal cell carcinoma (RCC). The patient was referred for evaluation due to the development of progressive jaundice, fatigue, and weight loss. A computed tomography (CT) scan of the abdomen revealed a 40 mm nodule located at the ampulla of Vater, accompanied by dilatation of the bile duct, indicative of obstructive jaundice. Additionally, ultrasonography identified a mass approximately 20 mm in size in the lateral portion of the left breast. The patient underwent a pancreatoduodenectomy to address the ampullary mass and a lumpectomy for the breast lesion. Histological examination of the resected specimens confirmed the diagnosis of metastases from RCC in both the ampulla of Vater and the breast. |
| format | Article |
| id | doaj-art-fcc4d26532234fcfba3a2b565e14bfa3 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-fcc4d26532234fcfba3a2b565e14bfa32025-08-20T05:32:59ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-08-011510.3389/fonc.2025.16041701604170Case Report: Late simultaneous metastasis of renal clear cell carcinoma to the ampulla and breastGuofeng Dai0Shuya Li1Lei Sun2Gangpu Wang3Department of Thyroid and Breast Surgery, The Fourth People’s Hospital of Jinan, Jinan, ChinaDepartment of Critical Care Medicine, The Fourth People’s Hospital of Jinan, Jinan, ChinaDepartment of Pathology, Shandong Public Health Clinical Center, Jinan, ChinaDepartment of Thyroid and Breast Surgery, The Fourth People’s Hospital of Jinan, Jinan, ChinaWe present the case of a 67-year-old female who developed simultaneous metastases to the ampulla of Vater and the breast. Her medical history is significant for a radical nephrectomy performed twenty-one years prior for renal cell carcinoma (RCC). The patient was referred for evaluation due to the development of progressive jaundice, fatigue, and weight loss. A computed tomography (CT) scan of the abdomen revealed a 40 mm nodule located at the ampulla of Vater, accompanied by dilatation of the bile duct, indicative of obstructive jaundice. Additionally, ultrasonography identified a mass approximately 20 mm in size in the lateral portion of the left breast. The patient underwent a pancreatoduodenectomy to address the ampullary mass and a lumpectomy for the breast lesion. Histological examination of the resected specimens confirmed the diagnosis of metastases from RCC in both the ampulla of Vater and the breast.https://www.frontiersin.org/articles/10.3389/fonc.2025.1604170/fullrenal cell carcinomaampullary massobstructive jaundicemetastatic breast cancercancer |
| spellingShingle | Guofeng Dai Shuya Li Lei Sun Gangpu Wang Case Report: Late simultaneous metastasis of renal clear cell carcinoma to the ampulla and breast Frontiers in Oncology renal cell carcinoma ampullary mass obstructive jaundice metastatic breast cancer cancer |
| title | Case Report: Late simultaneous metastasis of renal clear cell carcinoma to the ampulla and breast |
| title_full | Case Report: Late simultaneous metastasis of renal clear cell carcinoma to the ampulla and breast |
| title_fullStr | Case Report: Late simultaneous metastasis of renal clear cell carcinoma to the ampulla and breast |
| title_full_unstemmed | Case Report: Late simultaneous metastasis of renal clear cell carcinoma to the ampulla and breast |
| title_short | Case Report: Late simultaneous metastasis of renal clear cell carcinoma to the ampulla and breast |
| title_sort | case report late simultaneous metastasis of renal clear cell carcinoma to the ampulla and breast |
| topic | renal cell carcinoma ampullary mass obstructive jaundice metastatic breast cancer cancer |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1604170/full |
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