Upper Gastrointestinal Bleeding Secondary to Sodium Polystyrene Sulfonate Use: A Rare Adverse Effect of Commonly Prescribed Treatment
We report a case of a 62-year-old man who was brought in by emergency medical services after a fall and change in mental status. He was found to have severe hyperkalemia, acute kidney injury, and rhabdomyolysis. The hyperkalemia was treated with sodium polystyrene sulfonate (SPS). During hospitaliza...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2024/6004323 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832546172304097280 |
|---|---|
| author | Hamzah Shariff Shiva Naidoo Ghazal Ghafari Hongjie Li Manisha Devi Kishore Kumar |
| author_facet | Hamzah Shariff Shiva Naidoo Ghazal Ghafari Hongjie Li Manisha Devi Kishore Kumar |
| author_sort | Hamzah Shariff |
| collection | DOAJ |
| description | We report a case of a 62-year-old man who was brought in by emergency medical services after a fall and change in mental status. He was found to have severe hyperkalemia, acute kidney injury, and rhabdomyolysis. The hyperkalemia was treated with sodium polystyrene sulfonate (SPS). During hospitalization, he witnessed having black tarry stools along with a significant drop in hemoglobin. Endoscopic evaluation demonstrated nonbleeding large diffuse gastric ulcers with stigmata of recent bleeding, and ulcer biopsy revealed findings consistent with SPS-induced gastric ulceration. No other source of bleeding was localized, suggesting acute upper gastrointestinal bleeding due to SPS mucosal injury. |
| format | Article |
| id | doaj-art-fcb5d764d6114204973ffd815b608dc3 |
| institution | Kabale University |
| issn | 2090-6536 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-fcb5d764d6114204973ffd815b608dc32025-02-03T07:23:42ZengWileyCase Reports in Gastrointestinal Medicine2090-65362024-01-01202410.1155/2024/6004323Upper Gastrointestinal Bleeding Secondary to Sodium Polystyrene Sulfonate Use: A Rare Adverse Effect of Commonly Prescribed TreatmentHamzah Shariff0Shiva Naidoo1Ghazal Ghafari2Hongjie Li3Manisha Devi4Kishore Kumar5Geisinger Commonwealth School of MedicineDepartment of Internal MedicineDepartment of Clinical and Laboratory PathologyDepartment of Clinical and Laboratory PathologyDepartment of Internal MedicineDepartment of GastroenterologyWe report a case of a 62-year-old man who was brought in by emergency medical services after a fall and change in mental status. He was found to have severe hyperkalemia, acute kidney injury, and rhabdomyolysis. The hyperkalemia was treated with sodium polystyrene sulfonate (SPS). During hospitalization, he witnessed having black tarry stools along with a significant drop in hemoglobin. Endoscopic evaluation demonstrated nonbleeding large diffuse gastric ulcers with stigmata of recent bleeding, and ulcer biopsy revealed findings consistent with SPS-induced gastric ulceration. No other source of bleeding was localized, suggesting acute upper gastrointestinal bleeding due to SPS mucosal injury.http://dx.doi.org/10.1155/2024/6004323 |
| spellingShingle | Hamzah Shariff Shiva Naidoo Ghazal Ghafari Hongjie Li Manisha Devi Kishore Kumar Upper Gastrointestinal Bleeding Secondary to Sodium Polystyrene Sulfonate Use: A Rare Adverse Effect of Commonly Prescribed Treatment Case Reports in Gastrointestinal Medicine |
| title | Upper Gastrointestinal Bleeding Secondary to Sodium Polystyrene Sulfonate Use: A Rare Adverse Effect of Commonly Prescribed Treatment |
| title_full | Upper Gastrointestinal Bleeding Secondary to Sodium Polystyrene Sulfonate Use: A Rare Adverse Effect of Commonly Prescribed Treatment |
| title_fullStr | Upper Gastrointestinal Bleeding Secondary to Sodium Polystyrene Sulfonate Use: A Rare Adverse Effect of Commonly Prescribed Treatment |
| title_full_unstemmed | Upper Gastrointestinal Bleeding Secondary to Sodium Polystyrene Sulfonate Use: A Rare Adverse Effect of Commonly Prescribed Treatment |
| title_short | Upper Gastrointestinal Bleeding Secondary to Sodium Polystyrene Sulfonate Use: A Rare Adverse Effect of Commonly Prescribed Treatment |
| title_sort | upper gastrointestinal bleeding secondary to sodium polystyrene sulfonate use a rare adverse effect of commonly prescribed treatment |
| url | http://dx.doi.org/10.1155/2024/6004323 |
| work_keys_str_mv | AT hamzahshariff uppergastrointestinalbleedingsecondarytosodiumpolystyrenesulfonateusearareadverseeffectofcommonlyprescribedtreatment AT shivanaidoo uppergastrointestinalbleedingsecondarytosodiumpolystyrenesulfonateusearareadverseeffectofcommonlyprescribedtreatment AT ghazalghafari uppergastrointestinalbleedingsecondarytosodiumpolystyrenesulfonateusearareadverseeffectofcommonlyprescribedtreatment AT hongjieli uppergastrointestinalbleedingsecondarytosodiumpolystyrenesulfonateusearareadverseeffectofcommonlyprescribedtreatment AT manishadevi uppergastrointestinalbleedingsecondarytosodiumpolystyrenesulfonateusearareadverseeffectofcommonlyprescribedtreatment AT kishorekumar uppergastrointestinalbleedingsecondarytosodiumpolystyrenesulfonateusearareadverseeffectofcommonlyprescribedtreatment |