Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens
ABSTRACT Bacterial infections can induce exuberant immune responses that can damage host tissues. Previously, we demonstrated that systemic Escherichia coli infection in mice causes tissue damage in the liver. This liver necrosis is associated with the expression of endogenous retroviruses, chromoso...
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| Main Authors: | Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2025-02-01
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| Series: | mBio |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/mbio.03412-24 |
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