Association of Hsa_circ_0059511 with the sensitivity of the temozolomide chemotherapeutic treatment in human glioma cells

Association of Hsa_circ_0059511 with the sensitivity of the temozolomide chemotherapeutic treatment in human glioma cells

Abstract While surgical resection combined with temozolomide (TMZ) chemotherapy remains the cornerstone of glioma treatment, therapeutic efficacy is significantly limited by intrinsic and acquired TMZ resistance. This study identified elevated expression of circular RNA circ0059511 in TMZ-resistant...

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Bibliographic Details
Main Authors: Yiming Chen, Pingxin Cheng, Wei Huang, Yajun Jing, Jinye Su, Zanyi Wu, Jiawei Cai
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
circ0059511
Glioblastoma
miR-194-5p
Temozolomide resistance
Online Access:https://doi.org/10.1038/s41598-025-12492-8
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