Integration of transcriptome-wide association study and gene-based association analysis identifies candidate genes for Hodgkin lymphoma

Integration of transcriptome-wide association study and gene-based association analysis identifies candidate genes for Hodgkin lymphoma

Abstract Background Genome-wide association studies (GWASs) have pinpointed many susceptibility loci for Hodgkin Lymphoma (HL), but their underlying biological mechanisms remain unclear. Methods Utilizing GWAS data from the UK Biobank and FinnGen, along with expression quantitative trait loci (eQTL)...

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Main Authors: Wen-Hui Jia, Chang-Ling Huang, Wen-Li Zhang, Yong-Qiao He, Wen-Qiong Xue, Ying Liao, Zhi-Yang Zhao, Meng-Xuan Yang, Lu Pei, Wei-Hua Jia, Tong-Min Wang
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Journal of Cancer Research and Clinical Oncology
Subjects:
Hodgkin lymphoma
Susceptibility genes
Human leukocyte antigen
Online Access:https://doi.org/10.1007/s00432-025-06224-8
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https://doi.org/10.1007/s00432-025-06224-8

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