Geographical prevalence and risk factors for pterygium: a systematic review and meta-analysis
Objective Pterygium is considered to be a proliferative overgrowth of bulbar conjunctiva that can induce significant astigmatism and cause visual impairment; this is the first meta-analysis to investigate the pooled prevalence and risk factors for pterygium in the global world.Design A systematic re...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2013-11-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/3/11/e003787.full |
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| _version_ | 1832542554717945856 |
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| author | Zhe Yuan Lei Liu Jingyang Wu Desheng Huang Jin Geng |
| author_facet | Zhe Yuan Lei Liu Jingyang Wu Desheng Huang Jin Geng |
| author_sort | Zhe Yuan |
| collection | DOAJ |
| description | Objective Pterygium is considered to be a proliferative overgrowth of bulbar conjunctiva that can induce significant astigmatism and cause visual impairment; this is the first meta-analysis to investigate the pooled prevalence and risk factors for pterygium in the global world.Design A systematic review and meta-analysis of population-based studies.Setting International.Participants A total of 20 studies with 900 545 samples were included.Primary outcome measure The pooled prevalence and risk factors for pterygium.Results 20 studies were included. The pooled prevalence of pterygium was 10.2% (95% CI 6.3% to 16.1%). The pooled prevalence among men was higher than that among women (14.5% vs 13.6%). The proportion of participants with unilateral cases of pterygium was higher than that of participants with bilateral cases of pterygium. We found a trend that the higher pooled prevalence of pterygium was associated with increasing geographical latitude and age in the world. The pooled OR was 2.32 (95% CI 1.66 to 3.23) for the male gender and 1.76 (95% CI 1.55 to 2.00) for outdoor activity, respectively.Conclusions The pooled prevalence of pterygium was relatively high, especially for low latitude regions and the elderly. There were many modifiable risk factors associated with pterygium to which healthcare providers should pay more attention. |
| format | Article |
| id | doaj-art-fcab0d099fa742479cb88fd08d575108 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2013-11-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-fcab0d099fa742479cb88fd08d5751082025-02-04T02:55:09ZengBMJ Publishing GroupBMJ Open2044-60552013-11-0131110.1136/bmjopen-2013-003787Geographical prevalence and risk factors for pterygium: a systematic review and meta-analysisZhe Yuan0Lei Liu1Jingyang Wu2Desheng Huang3Jin Geng4Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA2 Department of Gastroenterology, Third Military Medical University, Chongqing, ChinaDepartment of Ophthalmology, The First Affiliated Hospital, China Medical University, Shenyang, ChinaDepartment of Epidemiology, School of Public Health, China Medical University, Shenyang, ChinaDepartment of Ophthalmology, The First Affiliated Hospital, China Medical University, Shenyang, ChinaObjective Pterygium is considered to be a proliferative overgrowth of bulbar conjunctiva that can induce significant astigmatism and cause visual impairment; this is the first meta-analysis to investigate the pooled prevalence and risk factors for pterygium in the global world.Design A systematic review and meta-analysis of population-based studies.Setting International.Participants A total of 20 studies with 900 545 samples were included.Primary outcome measure The pooled prevalence and risk factors for pterygium.Results 20 studies were included. The pooled prevalence of pterygium was 10.2% (95% CI 6.3% to 16.1%). The pooled prevalence among men was higher than that among women (14.5% vs 13.6%). The proportion of participants with unilateral cases of pterygium was higher than that of participants with bilateral cases of pterygium. We found a trend that the higher pooled prevalence of pterygium was associated with increasing geographical latitude and age in the world. The pooled OR was 2.32 (95% CI 1.66 to 3.23) for the male gender and 1.76 (95% CI 1.55 to 2.00) for outdoor activity, respectively.Conclusions The pooled prevalence of pterygium was relatively high, especially for low latitude regions and the elderly. There were many modifiable risk factors associated with pterygium to which healthcare providers should pay more attention.https://bmjopen.bmj.com/content/3/11/e003787.full |
| spellingShingle | Zhe Yuan Lei Liu Jingyang Wu Desheng Huang Jin Geng Geographical prevalence and risk factors for pterygium: a systematic review and meta-analysis BMJ Open |
| title | Geographical prevalence and risk factors for pterygium: a systematic review and meta-analysis |
| title_full | Geographical prevalence and risk factors for pterygium: a systematic review and meta-analysis |
| title_fullStr | Geographical prevalence and risk factors for pterygium: a systematic review and meta-analysis |
| title_full_unstemmed | Geographical prevalence and risk factors for pterygium: a systematic review and meta-analysis |
| title_short | Geographical prevalence and risk factors for pterygium: a systematic review and meta-analysis |
| title_sort | geographical prevalence and risk factors for pterygium a systematic review and meta analysis |
| url | https://bmjopen.bmj.com/content/3/11/e003787.full |
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