Executive dysfunction in affective disorders: differences in bipolar affective disorder and depressive episode
Aim. To identify the differences in executive function (inhibitory control, working memory, cognitive flexibility) between patients with bipolar affective disorder and depressive episode.Materials and methods. A total of 72 patients with affective disorders aged 20–40 years were examined. Of them, 3...
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| Language: | English |
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Siberian State Medical University (Tomsk)
2022-10-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/4900 |
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| author | S. A. Galkin S. N. Vasilieva G. G. Simutkin S. A. Ivanova |
| author_facet | S. A. Galkin S. N. Vasilieva G. G. Simutkin S. A. Ivanova |
| author_sort | S. A. Galkin |
| collection | DOAJ |
| description | Aim. To identify the differences in executive function (inhibitory control, working memory, cognitive flexibility) between patients with bipolar affective disorder and depressive episode.Materials and methods. A total of 72 patients with affective disorders aged 20–40 years were examined. Of them, 30 patients had bipolar affective disorder, a current episode of mild or moderate depression, and 42 patients had a mild, moderate, and severe depressive episode without symptoms of psychosis. The executive function was evaluated using PsyToolkit, a set of software tools for programming psychological experiments. Computerized Go/ No–go tasks (assessment of inhibitory control and psychomotor functions), the Corsi block-tapping test (assessment of visual and spatial working memory capacities), and the Stroop Color and Word Test (assessment of cognitive flexibility) were used.Results. An intergroup comparison of patients revealed that patients with bipolar disorder significantly more often demonstrated false button press in the Go/No–go task (p = 0.043); however, they exhibited a greater working memory capacity in the Corsi block-tapping test (p = 0.049) compared with patients with a depressive episode.Conclusion. Important data were obtained regarding the specifics of executive dysfunction depending on the type of affective disorder. The presented data expand and supplement available information about the cognitive characteristics of patients with bipolar affective disorder and depressive episode, which may be useful in clinical practice and serve a focus of future research. |
| format | Article |
| id | doaj-art-fc820b1d8ba944aa9a92b1eef53bd861 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2022-10-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-fc820b1d8ba944aa9a92b1eef53bd8612025-08-20T03:37:41ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842022-10-01213283310.20538/1682-0363-2022-3-28-332911Executive dysfunction in affective disorders: differences in bipolar affective disorder and depressive episodeS. A. Galkin0S. N. Vasilieva1G. G. Simutkin2S. A. Ivanova3Mental Health Research Institute, Tomsk National Research Medical Center (NRMC), Russian Academy of SciencesMental Health Research Institute, Tomsk National Research Medical Center (NRMC), Russian Academy of SciencesMental Health Research Institute, Tomsk National Research Medical Center (NRMC), Russian Academy of SciencesMental Health Research Institute, Tomsk National Research Medical Center (NRMC), Russian Academy of Sciences; Siberian State Medical UniversityAim. To identify the differences in executive function (inhibitory control, working memory, cognitive flexibility) between patients with bipolar affective disorder and depressive episode.Materials and methods. A total of 72 patients with affective disorders aged 20–40 years were examined. Of them, 30 patients had bipolar affective disorder, a current episode of mild or moderate depression, and 42 patients had a mild, moderate, and severe depressive episode without symptoms of psychosis. The executive function was evaluated using PsyToolkit, a set of software tools for programming psychological experiments. Computerized Go/ No–go tasks (assessment of inhibitory control and psychomotor functions), the Corsi block-tapping test (assessment of visual and spatial working memory capacities), and the Stroop Color and Word Test (assessment of cognitive flexibility) were used.Results. An intergroup comparison of patients revealed that patients with bipolar disorder significantly more often demonstrated false button press in the Go/No–go task (p = 0.043); however, they exhibited a greater working memory capacity in the Corsi block-tapping test (p = 0.049) compared with patients with a depressive episode.Conclusion. Important data were obtained regarding the specifics of executive dysfunction depending on the type of affective disorder. The presented data expand and supplement available information about the cognitive characteristics of patients with bipolar affective disorder and depressive episode, which may be useful in clinical practice and serve a focus of future research.https://bulletin.ssmu.ru/jour/article/view/4900affective disordersbipolar affective disorderdepressive episodeexecutive functioncognitive deficit |
| spellingShingle | S. A. Galkin S. N. Vasilieva G. G. Simutkin S. A. Ivanova Executive dysfunction in affective disorders: differences in bipolar affective disorder and depressive episode Бюллетень сибирской медицины affective disorders bipolar affective disorder depressive episode executive function cognitive deficit |
| title | Executive dysfunction in affective disorders: differences in bipolar affective disorder and depressive episode |
| title_full | Executive dysfunction in affective disorders: differences in bipolar affective disorder and depressive episode |
| title_fullStr | Executive dysfunction in affective disorders: differences in bipolar affective disorder and depressive episode |
| title_full_unstemmed | Executive dysfunction in affective disorders: differences in bipolar affective disorder and depressive episode |
| title_short | Executive dysfunction in affective disorders: differences in bipolar affective disorder and depressive episode |
| title_sort | executive dysfunction in affective disorders differences in bipolar affective disorder and depressive episode |
| topic | affective disorders bipolar affective disorder depressive episode executive function cognitive deficit |
| url | https://bulletin.ssmu.ru/jour/article/view/4900 |
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