Pair combinations of human monoclonal antibodies fully protected mice against bunyavirus SFTSV lethal challenge.

Severe fever with thrombocytopenia syndrome (SFTS) is a viral hemorrhagic fever caused by a tick-borne virus SFTSV with a mortality rate of up to 30%. Currently, there is no vaccine or effective therapy for SFTS. Neutralizing monoclonal antibody therapy, which provides immediate passive immunity and...

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Main Authors: Bang Li, Xiang-Rong Qin, Jia-Chen Qu, Guan-du Wu, Wen-Kang Zhang, Ze-Zheng Jiang, Pan-Pan Liu, Ze-Min Li, Tian-Mei Yu, Chuan-Min Zhou, Yong-Jun Jiao, Xue-Jie Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012889
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