Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic Pitfall
Axillary nodal metastasis from a nonmammary neoplasia is much rarer than diseases associated with a primary breast carcinoma. However, this has to be considered in the differential diagnosis of nodal disease in patients with a history of breast cancer. Here, we report the case of a 73-year-old femal...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2014/534034 |
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| author | Chantal Atallah Gulbeyaz Altinel Lili Fu Jocelyne Arseneau Atilla Omeroglu |
| author_facet | Chantal Atallah Gulbeyaz Altinel Lili Fu Jocelyne Arseneau Atilla Omeroglu |
| author_sort | Chantal Atallah |
| collection | DOAJ |
| description | Axillary nodal metastasis from a nonmammary neoplasia is much rarer than diseases associated with a primary breast carcinoma. However, this has to be considered in the differential diagnosis of nodal disease in patients with a history of breast cancer. Here, we report the case of a 73-year-old female with a past medical history of breast cancer, presenting with an ipsilateral axillary metastatic carcinoma. The immunohistochemical profile of the metastatic lesion was consistent with a high grade serous carcinoma. After undergoing a total abdominal hysterectomy and salpingo-oophorectomy, thorough pathological examination revealed two microscopic foci of serous carcinoma in the right fallopian tube, not detectable by preoperative magnetic resonance imaging. In this context, the poorly differentiated appearance of the metastatic tumor and positive staining for estrogen receptor, might lead to a misdiagnosis of metastatic breast carcinoma. As the therapeutic implications differ, it is important for the pathologist to critically assess axillary lymph node metastases, even in patients with a past history of ipsilateral breast carcinoma and no other known primary tumors. |
| format | Article |
| id | doaj-art-fc66e239a31742d08d6ef7c7589347d4 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-fc66e239a31742d08d6ef7c7589347d42025-02-03T01:31:07ZengWileyCase Reports in Pathology2090-67812090-679X2014-01-01201410.1155/2014/534034534034Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic PitfallChantal Atallah0Gulbeyaz Altinel1Lili Fu2Jocelyne Arseneau3Atilla Omeroglu4McGill University Health Center, Montreal, QC, H3A 1A1, CanadaMcGill University Health Center, Montreal, QC, H3A 1A1, CanadaMcGill University Health Center, Montreal, QC, H3A 1A1, CanadaMcGill University Health Center, Montreal, QC, H3A 1A1, CanadaMcGill University Health Center, Montreal, QC, H3A 1A1, CanadaAxillary nodal metastasis from a nonmammary neoplasia is much rarer than diseases associated with a primary breast carcinoma. However, this has to be considered in the differential diagnosis of nodal disease in patients with a history of breast cancer. Here, we report the case of a 73-year-old female with a past medical history of breast cancer, presenting with an ipsilateral axillary metastatic carcinoma. The immunohistochemical profile of the metastatic lesion was consistent with a high grade serous carcinoma. After undergoing a total abdominal hysterectomy and salpingo-oophorectomy, thorough pathological examination revealed two microscopic foci of serous carcinoma in the right fallopian tube, not detectable by preoperative magnetic resonance imaging. In this context, the poorly differentiated appearance of the metastatic tumor and positive staining for estrogen receptor, might lead to a misdiagnosis of metastatic breast carcinoma. As the therapeutic implications differ, it is important for the pathologist to critically assess axillary lymph node metastases, even in patients with a past history of ipsilateral breast carcinoma and no other known primary tumors.http://dx.doi.org/10.1155/2014/534034 |
| spellingShingle | Chantal Atallah Gulbeyaz Altinel Lili Fu Jocelyne Arseneau Atilla Omeroglu Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic Pitfall Case Reports in Pathology |
| title | Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic Pitfall |
| title_full | Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic Pitfall |
| title_fullStr | Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic Pitfall |
| title_full_unstemmed | Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic Pitfall |
| title_short | Axillary Metastasis from an Occult Tubal Serous Carcinoma in a Patient with Ipsilateral Breast Carcinoma: A Potential Diagnostic Pitfall |
| title_sort | axillary metastasis from an occult tubal serous carcinoma in a patient with ipsilateral breast carcinoma a potential diagnostic pitfall |
| url | http://dx.doi.org/10.1155/2014/534034 |
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