Prognostic Factors for the Development of Biochemical Recurrence after Radical Prostatectomy

Prostate cancer is one of the most common cancers in Western countries and is associated with a considerable risk of mortality. Biochemical recurrence following radical prostatectomy is a relatively common finding, affecting approximately 25% of cases. The aim of our paper was to identify factors th...

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Main Authors: Ahmed F. Kotb, Ahmed A. Elabbady
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/2011/485189
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author Ahmed F. Kotb
Ahmed A. Elabbady
author_facet Ahmed F. Kotb
Ahmed A. Elabbady
author_sort Ahmed F. Kotb
collection DOAJ
description Prostate cancer is one of the most common cancers in Western countries and is associated with a considerable risk of mortality. Biochemical recurrence following radical prostatectomy is a relatively common finding, affecting approximately 25% of cases. The aim of our paper was to identify factors that can predict the occurrence of biochemical recurrence, so the patient can be properly counselled pre- and postoperatively. Medline review of the literatures was done followed by a group discussion on the chosen publications and their valuable influence. Preoperative serum total PSA and clinical stage, together with prostatectomy Gleason grade, tumour volume, and perineural and vascular invasions, were the most important variables found to influence outcome.
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spelling doaj-art-fc4f5dc0bb0e4053a5c1489e55023d0c2025-02-03T05:59:20ZengWileyProstate Cancer2090-31112090-312X2011-01-01201110.1155/2011/485189485189Prognostic Factors for the Development of Biochemical Recurrence after Radical ProstatectomyAhmed F. Kotb0Ahmed A. Elabbady1Urology Department, Faculty of Medicine, Alexandria University, Alexandria, EgyptUrology Department, Faculty of Medicine, Alexandria University, Alexandria, EgyptProstate cancer is one of the most common cancers in Western countries and is associated with a considerable risk of mortality. Biochemical recurrence following radical prostatectomy is a relatively common finding, affecting approximately 25% of cases. The aim of our paper was to identify factors that can predict the occurrence of biochemical recurrence, so the patient can be properly counselled pre- and postoperatively. Medline review of the literatures was done followed by a group discussion on the chosen publications and their valuable influence. Preoperative serum total PSA and clinical stage, together with prostatectomy Gleason grade, tumour volume, and perineural and vascular invasions, were the most important variables found to influence outcome.http://dx.doi.org/10.1155/2011/485189
spellingShingle Ahmed F. Kotb
Ahmed A. Elabbady
Prognostic Factors for the Development of Biochemical Recurrence after Radical Prostatectomy
Prostate Cancer
title Prognostic Factors for the Development of Biochemical Recurrence after Radical Prostatectomy
title_full Prognostic Factors for the Development of Biochemical Recurrence after Radical Prostatectomy
title_fullStr Prognostic Factors for the Development of Biochemical Recurrence after Radical Prostatectomy
title_full_unstemmed Prognostic Factors for the Development of Biochemical Recurrence after Radical Prostatectomy
title_short Prognostic Factors for the Development of Biochemical Recurrence after Radical Prostatectomy
title_sort prognostic factors for the development of biochemical recurrence after radical prostatectomy
url http://dx.doi.org/10.1155/2011/485189
work_keys_str_mv AT ahmedfkotb prognosticfactorsforthedevelopmentofbiochemicalrecurrenceafterradicalprostatectomy
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