Advances and prospects of precision nanomedicine in personalized tumor theranostics

Tumor, as the second leading cause of death globally, following closely behind cardiovascular diseases, remains a significant health challenge worldwide. Despite the existence of various cancer treatment methods, their efficacy is still suboptimal, necessitating the development of safer and more eff...

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Main Authors: Yuhang Mao, Juanping Xie, Fang Yang, Yan Luo, Juan Du, Hong Xiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1514399/full
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author Yuhang Mao
Yuhang Mao
Yuhang Mao
Juanping Xie
Juanping Xie
Fang Yang
Yan Luo
Juan Du
Hong Xiang
author_facet Yuhang Mao
Yuhang Mao
Yuhang Mao
Juanping Xie
Juanping Xie
Fang Yang
Yan Luo
Juan Du
Hong Xiang
author_sort Yuhang Mao
collection DOAJ
description Tumor, as the second leading cause of death globally, following closely behind cardiovascular diseases, remains a significant health challenge worldwide. Despite the existence of various cancer treatment methods, their efficacy is still suboptimal, necessitating the development of safer and more efficient treatment strategies. Additionally, the advancement of personalized therapy offers further possibilities in cancer treatment. Nanomedicine, as a promising interdisciplinary field, has shown tremendous potential and prospects in the diagnosis and treatment of cancer. As an emerging approach in oncology, the application of nanomedicine in personalized cancer therapy primarily focuses on targeted drug delivery systems such as passive targeting drug delivery, active targeting drug delivery, and environmentally responsive targeting drug delivery, as well as imaging diagnostics such as tumor biomarker detection, tumor cell detection, and in vivo imaging. However, it still faces challenges regarding safety, biocompatibility, and other issues. This review aims to explore the advances in the use of nanomaterials in the field of personalized cancer diagnosis and treatment and to investigate the prospects and challenges of developing personalized therapies in cancer care, providing direction for the clinical translation and application.
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publisher Frontiers Media S.A.
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series Frontiers in Cell and Developmental Biology
spelling doaj-art-fc40d11ef8014e369b2c8ea4f7bdfffc2025-08-20T02:18:57ZengFrontiers Media S.A.Frontiers in Cell and Developmental Biology2296-634X2024-12-011210.3389/fcell.2024.15143991514399Advances and prospects of precision nanomedicine in personalized tumor theranosticsYuhang Mao0Yuhang Mao1Yuhang Mao2Juanping Xie3Juanping Xie4Fang Yang5Yan Luo6Juan Du7Hong Xiang8School of Medicine, Ankang University, Ankang, ChinaUltrasound Medicine Department, Ankang Traditional Chinese Medicine Hospital, Ankang, ChinaShanxi Province Engineering and Technology Research Center for Development and Utilization of Qinba Traditional Chinese Medicine Resources, Ankang University, Ankang, ChinaSchool of Medicine, Ankang University, Ankang, ChinaShanxi Province Engineering and Technology Research Center for Development and Utilization of Qinba Traditional Chinese Medicine Resources, Ankang University, Ankang, ChinaSchool of Modern Agriculture and Biotechnology, Ankang University, Ankang, ChinaSchool of Medicine, Ankang University, Ankang, ChinaDepartment of Stomatology, Hengqin Hospital, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, ChinaUltrasound Medicine Department, Ankang Traditional Chinese Medicine Hospital, Ankang, ChinaTumor, as the second leading cause of death globally, following closely behind cardiovascular diseases, remains a significant health challenge worldwide. Despite the existence of various cancer treatment methods, their efficacy is still suboptimal, necessitating the development of safer and more efficient treatment strategies. Additionally, the advancement of personalized therapy offers further possibilities in cancer treatment. Nanomedicine, as a promising interdisciplinary field, has shown tremendous potential and prospects in the diagnosis and treatment of cancer. As an emerging approach in oncology, the application of nanomedicine in personalized cancer therapy primarily focuses on targeted drug delivery systems such as passive targeting drug delivery, active targeting drug delivery, and environmentally responsive targeting drug delivery, as well as imaging diagnostics such as tumor biomarker detection, tumor cell detection, and in vivo imaging. However, it still faces challenges regarding safety, biocompatibility, and other issues. This review aims to explore the advances in the use of nanomaterials in the field of personalized cancer diagnosis and treatment and to investigate the prospects and challenges of developing personalized therapies in cancer care, providing direction for the clinical translation and application.https://www.frontiersin.org/articles/10.3389/fcell.2024.1514399/fulltumorpersonalized medicinenanomedicinetreatmentdiagnosis
spellingShingle Yuhang Mao
Yuhang Mao
Yuhang Mao
Juanping Xie
Juanping Xie
Fang Yang
Yan Luo
Juan Du
Hong Xiang
Advances and prospects of precision nanomedicine in personalized tumor theranostics
Frontiers in Cell and Developmental Biology
tumor
personalized medicine
nanomedicine
treatment
diagnosis
title Advances and prospects of precision nanomedicine in personalized tumor theranostics
title_full Advances and prospects of precision nanomedicine in personalized tumor theranostics
title_fullStr Advances and prospects of precision nanomedicine in personalized tumor theranostics
title_full_unstemmed Advances and prospects of precision nanomedicine in personalized tumor theranostics
title_short Advances and prospects of precision nanomedicine in personalized tumor theranostics
title_sort advances and prospects of precision nanomedicine in personalized tumor theranostics
topic tumor
personalized medicine
nanomedicine
treatment
diagnosis
url https://www.frontiersin.org/articles/10.3389/fcell.2024.1514399/full
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