Effectiveness & mechanism of phytoconstituents against Candida biofilm
Fungal biofilms are complex and resistant structures that pose a challenge in treating infections. Active phytoconstituents are natural compounds derived from plants that have shown promising antifungal properties. Many reports of antimicrobial resistance in human pathogenic fungi demand immediate...
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| Format: | Article |
| Language: | English |
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Action for Sustainable Efficacious Development and Awareness
2024-11-01
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| Series: | Environment Conservation Journal |
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| Online Access: | https://journal.environcj.in/index.php/ecj/article/view/3060 |
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| author | Madhulika Jha Jahanvi Agarwal Pankaj Gautam Navin Kumar |
| author_facet | Madhulika Jha Jahanvi Agarwal Pankaj Gautam Navin Kumar |
| author_sort | Madhulika Jha |
| collection | DOAJ |
| description |
Fungal biofilms are complex and resistant structures that pose a challenge in treating infections. Active phytoconstituents are natural compounds derived from plants that have shown promising antifungal properties. Many reports of antimicrobial resistance in human pathogenic fungi demand immediate attention to explore new therapeutics. Plant-based therapeutics alone or in conjugated form have shown promising results against fungal biofilms. Several studies have reported the effectiveness of various phyto constituents in inhibiting the formation and dispersal of fungal biofilm. Different mechanisms, such as disrupting cell signaling pathways, inhibiting biofilm matrix formation, and altering the fungal cell wall structure, have demonstrated the effectiveness of these compounds. This review focuses on the use of active phytoconstituents as potential agents against fungal biofilm.
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| format | Article |
| id | doaj-art-fbea37fdf45c447ea374f21f2dfef9dc |
| institution | DOAJ |
| issn | 0972-3099 2278-5124 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Action for Sustainable Efficacious Development and Awareness |
| record_format | Article |
| series | Environment Conservation Journal |
| spelling | doaj-art-fbea37fdf45c447ea374f21f2dfef9dc2025-08-20T02:40:04ZengAction for Sustainable Efficacious Development and AwarenessEnvironment Conservation Journal0972-30992278-51242024-11-0125410.36953/ECJ.30601324Effectiveness & mechanism of phytoconstituents against Candida biofilmMadhulika Jha0Jahanvi Agarwal 1Pankaj Gautam2Navin Kumar3Department of Biotechnology, Graphic Era (Deemed to be University), Clement Town, Dehradun-248002Department of Biotechnology, Graphic Era (Deemed to be University), Clement Town, Dehradun-248002Department of Microbiology, Graphic Era (Deemed to be University), Clement Town, Dehradun-248002Department of Biotechnology, Graphic Era (Deemed to be University), Clement Town, Dehradun-248002 Fungal biofilms are complex and resistant structures that pose a challenge in treating infections. Active phytoconstituents are natural compounds derived from plants that have shown promising antifungal properties. Many reports of antimicrobial resistance in human pathogenic fungi demand immediate attention to explore new therapeutics. Plant-based therapeutics alone or in conjugated form have shown promising results against fungal biofilms. Several studies have reported the effectiveness of various phyto constituents in inhibiting the formation and dispersal of fungal biofilm. Different mechanisms, such as disrupting cell signaling pathways, inhibiting biofilm matrix formation, and altering the fungal cell wall structure, have demonstrated the effectiveness of these compounds. This review focuses on the use of active phytoconstituents as potential agents against fungal biofilm. https://journal.environcj.in/index.php/ecj/article/view/3060AntifungalBiofilmCandidaMode of actionPlant-derived compounds |
| spellingShingle | Madhulika Jha Jahanvi Agarwal Pankaj Gautam Navin Kumar Effectiveness & mechanism of phytoconstituents against Candida biofilm Environment Conservation Journal Antifungal Biofilm Candida Mode of action Plant-derived compounds |
| title | Effectiveness & mechanism of phytoconstituents against Candida biofilm |
| title_full | Effectiveness & mechanism of phytoconstituents against Candida biofilm |
| title_fullStr | Effectiveness & mechanism of phytoconstituents against Candida biofilm |
| title_full_unstemmed | Effectiveness & mechanism of phytoconstituents against Candida biofilm |
| title_short | Effectiveness & mechanism of phytoconstituents against Candida biofilm |
| title_sort | effectiveness mechanism of phytoconstituents against candida biofilm |
| topic | Antifungal Biofilm Candida Mode of action Plant-derived compounds |
| url | https://journal.environcj.in/index.php/ecj/article/view/3060 |
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