Giant Condyloma Acuminata in Indonesian Females with SLE under Immunosuppressant and Steroid Therapy
Introduction. Immunosuppressant and steroid therapy in systemic lupus erythematosus (SLE) increases the risk of human papillomavirus (HPV) infections, one of which is giant condyloma acuminata (GCA). To our knowledge, there is no report evaluating the correlation between immunosuppressive and steroi...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Case Reports in Immunology |
| Online Access: | http://dx.doi.org/10.1155/2016/4710979 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849469203752419328 |
|---|---|
| author | Andhika Rachman Nabila Hasan |
| author_facet | Andhika Rachman Nabila Hasan |
| author_sort | Andhika Rachman |
| collection | DOAJ |
| description | Introduction. Immunosuppressant and steroid therapy in systemic lupus erythematosus (SLE) increases the risk of human papillomavirus (HPV) infections, one of which is giant condyloma acuminata (GCA). To our knowledge, there is no report evaluating the correlation between immunosuppressive and steroid therapy in patients with SLE and the prevalence of GCA. Case Report. A 42-year-old female was diagnosed with SLE a year ago and has been treated with steroids and immunosuppressive drugs. In the last few months she presented GCA involving the genital area recurring almost every two months. Type 6 and 11 HPVs were identified in vulva, vagina, and cervix. Methods. PubMed, EBSCO, and Cochrane Library literature were searched from inception to July 2015. Authors screened all titles and abstracts and read full text article, and two case-control studies were found relevant. Results. SLE patients in both studies were under immunosuppressive and steroid therapy. Condyloma acuminata was diagnosed at 108 months (latest) and 1 month (earliest) after SLE. Type 6, 11, 16, 42, and oncogenic group of HPV were identified. Conclusions. GCA is a type of HPV infection seldom observed in SLE patients. Therefore, their correlation is still unclear. Period of time since SLE was diagnosed and GCA varies from months to years. A more thorough physical and laboratory examination leading to HPV and other infectious disease is recommended. |
| format | Article |
| id | doaj-art-fbd14077f35848b2bbb431d8fecca3fa |
| institution | Kabale University |
| issn | 2090-6609 2090-6617 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Immunology |
| spelling | doaj-art-fbd14077f35848b2bbb431d8fecca3fa2025-08-20T03:25:34ZengWileyCase Reports in Immunology2090-66092090-66172016-01-01201610.1155/2016/47109794710979Giant Condyloma Acuminata in Indonesian Females with SLE under Immunosuppressant and Steroid TherapyAndhika Rachman0Nabila Hasan1Division of Hematology and Medical Oncology, Department of Internal Medicine, Faculty of Medicine, University of Indonesia-Cipto Mangunkusumo Hospital, Jakarta, IndonesiaFaculty of Medicine, University of Indonesia-Cipto Mangunkusumo Hospital, Jakarta, IndonesiaIntroduction. Immunosuppressant and steroid therapy in systemic lupus erythematosus (SLE) increases the risk of human papillomavirus (HPV) infections, one of which is giant condyloma acuminata (GCA). To our knowledge, there is no report evaluating the correlation between immunosuppressive and steroid therapy in patients with SLE and the prevalence of GCA. Case Report. A 42-year-old female was diagnosed with SLE a year ago and has been treated with steroids and immunosuppressive drugs. In the last few months she presented GCA involving the genital area recurring almost every two months. Type 6 and 11 HPVs were identified in vulva, vagina, and cervix. Methods. PubMed, EBSCO, and Cochrane Library literature were searched from inception to July 2015. Authors screened all titles and abstracts and read full text article, and two case-control studies were found relevant. Results. SLE patients in both studies were under immunosuppressive and steroid therapy. Condyloma acuminata was diagnosed at 108 months (latest) and 1 month (earliest) after SLE. Type 6, 11, 16, 42, and oncogenic group of HPV were identified. Conclusions. GCA is a type of HPV infection seldom observed in SLE patients. Therefore, their correlation is still unclear. Period of time since SLE was diagnosed and GCA varies from months to years. A more thorough physical and laboratory examination leading to HPV and other infectious disease is recommended.http://dx.doi.org/10.1155/2016/4710979 |
| spellingShingle | Andhika Rachman Nabila Hasan Giant Condyloma Acuminata in Indonesian Females with SLE under Immunosuppressant and Steroid Therapy Case Reports in Immunology |
| title | Giant Condyloma Acuminata in Indonesian Females with SLE under Immunosuppressant and Steroid Therapy |
| title_full | Giant Condyloma Acuminata in Indonesian Females with SLE under Immunosuppressant and Steroid Therapy |
| title_fullStr | Giant Condyloma Acuminata in Indonesian Females with SLE under Immunosuppressant and Steroid Therapy |
| title_full_unstemmed | Giant Condyloma Acuminata in Indonesian Females with SLE under Immunosuppressant and Steroid Therapy |
| title_short | Giant Condyloma Acuminata in Indonesian Females with SLE under Immunosuppressant and Steroid Therapy |
| title_sort | giant condyloma acuminata in indonesian females with sle under immunosuppressant and steroid therapy |
| url | http://dx.doi.org/10.1155/2016/4710979 |
| work_keys_str_mv | AT andhikarachman giantcondylomaacuminatainindonesianfemaleswithsleunderimmunosuppressantandsteroidtherapy AT nabilahasan giantcondylomaacuminatainindonesianfemaleswithsleunderimmunosuppressantandsteroidtherapy |