Computational Elucidation of Human β‑Defensin‑2 as a Dual Inhibitor of MMP‑9 and PKC-βII for Diabetic Wound Management

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Main Authors: Vidyasrilekha Sanapalli, Dilep Kumar Sigalapalli, Afzal B. Shaik, Richie R. Bhandare, Bharat Kumar Reddy Sanapalli
Format: Article
Language:English
Published: American Chemical Society 2025-01-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.4c08292
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author Vidyasrilekha Sanapalli
Dilep Kumar Sigalapalli
Afzal B. Shaik
Richie R. Bhandare
Bharat Kumar Reddy Sanapalli
author_facet Vidyasrilekha Sanapalli
Dilep Kumar Sigalapalli
Afzal B. Shaik
Richie R. Bhandare
Bharat Kumar Reddy Sanapalli
author_sort Vidyasrilekha Sanapalli
collection DOAJ
format Article
id doaj-art-fbc3fe42dac6432594b566ab809d3af0
institution Kabale University
issn 2470-1343
language English
publishDate 2025-01-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-fbc3fe42dac6432594b566ab809d3af02025-02-04T09:11:34ZengAmerican Chemical SocietyACS Omega2470-13432025-01-011043575358410.1021/acsomega.4c08292Computational Elucidation of Human β‑Defensin‑2 as a Dual Inhibitor of MMP‑9 and PKC-βII for Diabetic Wound ManagementVidyasrilekha Sanapalli0Dilep Kumar Sigalapalli1Afzal B. Shaik2Richie R. Bhandare3Bharat Kumar Reddy Sanapalli4Department of Pharmaceutical Chemistry, School of Pharmacy & Technology Management, SVKM’s Narsee Monjee Institute of Management Studies (NMIMS) Deemed to be University, Jadcherla, Telangana, IndiaDepartment of Pharmaceutical Chemistry, Vignan Pharmacy College, Jawaharlal Nehru Technological University, Guntur, Andhra Pradesh, IndiaDepartment of Pharmaceutical Sciences, School of Biotechnology and Pharmaceutical Sciences, Vignan’s Foundation for Science, Technology & Research, Guntur, Andhra Pradesh, IndiaDepartment of Pharmaceutical Sciences, College of Pharmacy & Health Sciences, Ajman University, Ajman, UAEDepartment of Pharmacology, School of Pharmacy & Technology Management, SVKM’s Narsee Monjee Institute of Management Studies (NMIMS) Deemed to be University, Jadcherla, Telangana, Indiahttps://doi.org/10.1021/acsomega.4c08292
spellingShingle Vidyasrilekha Sanapalli
Dilep Kumar Sigalapalli
Afzal B. Shaik
Richie R. Bhandare
Bharat Kumar Reddy Sanapalli
Computational Elucidation of Human β‑Defensin‑2 as a Dual Inhibitor of MMP‑9 and PKC-βII for Diabetic Wound Management
ACS Omega
title Computational Elucidation of Human β‑Defensin‑2 as a Dual Inhibitor of MMP‑9 and PKC-βII for Diabetic Wound Management
title_full Computational Elucidation of Human β‑Defensin‑2 as a Dual Inhibitor of MMP‑9 and PKC-βII for Diabetic Wound Management
title_fullStr Computational Elucidation of Human β‑Defensin‑2 as a Dual Inhibitor of MMP‑9 and PKC-βII for Diabetic Wound Management
title_full_unstemmed Computational Elucidation of Human β‑Defensin‑2 as a Dual Inhibitor of MMP‑9 and PKC-βII for Diabetic Wound Management
title_short Computational Elucidation of Human β‑Defensin‑2 as a Dual Inhibitor of MMP‑9 and PKC-βII for Diabetic Wound Management
title_sort computational elucidation of human β defensin 2 as a dual inhibitor of mmp 9 and pkc βii for diabetic wound management
url https://doi.org/10.1021/acsomega.4c08292
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