Primary mucinous adenocarcinoma of the ureter and renal pelvis: A case report
Primary adenocarcinoma rarely occurs in the upper urinary tract and accounts for less than 1% of the urothelial tumors. Here we present a case report of a 45-year-old female patient who presented with a lump in the abdomen and pain in the right lumbar region for 2 months. Various radiological invest...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
|
| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_575_22 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841550049770733568 |
|---|---|
| author | Aparna A. N. Namshiker Amala J. Kudchadker R. G. Wiseman Pinto |
| author_facet | Aparna A. N. Namshiker Amala J. Kudchadker R. G. Wiseman Pinto |
| author_sort | Aparna A. N. Namshiker |
| collection | DOAJ |
| description | Primary adenocarcinoma rarely occurs in the upper urinary tract and accounts for less than 1% of the urothelial tumors. Here we present a case report of a 45-year-old female patient who presented with a lump in the abdomen and pain in the right lumbar region for 2 months. Various radiological investigations revealed right-sided hydronephrosis with enhancing masses in the right proximal ureter and renal pelvis associated with multiple calculi. A gross examination of the right nephrectomy specimen revealed multiple cystic areas filled with mucinous material and papillary projections in the renal pelvis. A necrotic growth was observed in the right proximal ureter in association with the staghorn calculus in the renal pelvis. Histological examination of the ureteric mass and solid areas from the renal pelvis showed acini and papillary projections lined by pseudostratified columnar epithelium showing malignant changes. Surrounding areas also revealed intestinal metaplasia with moderate to marked dysplasia in some places. The ureteric malignancy was observed to infiltrate the inner two-thirds of the wall of the ureteric muscular layer and extend until the margin of excision. Thus, a diagnosis of mucinous adenocarcinoma of the ureter and renal pelvis with intestinal metaplasia and dysplasia that occurred in association with a large staghorn calculus was made. |
| format | Article |
| id | doaj-art-fba2f957e99341ed8809c044ee93bff2 |
| institution | Kabale University |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-fba2f957e99341ed8809c044ee93bff22025-01-10T10:28:26ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-12-0167492492710.4103/ijpm.ijpm_575_22Primary mucinous adenocarcinoma of the ureter and renal pelvis: A case reportAparna A. N. NamshikerAmala J. KudchadkerR. G. Wiseman PintoPrimary adenocarcinoma rarely occurs in the upper urinary tract and accounts for less than 1% of the urothelial tumors. Here we present a case report of a 45-year-old female patient who presented with a lump in the abdomen and pain in the right lumbar region for 2 months. Various radiological investigations revealed right-sided hydronephrosis with enhancing masses in the right proximal ureter and renal pelvis associated with multiple calculi. A gross examination of the right nephrectomy specimen revealed multiple cystic areas filled with mucinous material and papillary projections in the renal pelvis. A necrotic growth was observed in the right proximal ureter in association with the staghorn calculus in the renal pelvis. Histological examination of the ureteric mass and solid areas from the renal pelvis showed acini and papillary projections lined by pseudostratified columnar epithelium showing malignant changes. Surrounding areas also revealed intestinal metaplasia with moderate to marked dysplasia in some places. The ureteric malignancy was observed to infiltrate the inner two-thirds of the wall of the ureteric muscular layer and extend until the margin of excision. Thus, a diagnosis of mucinous adenocarcinoma of the ureter and renal pelvis with intestinal metaplasia and dysplasia that occurred in association with a large staghorn calculus was made.https://journals.lww.com/10.4103/ijpm.ijpm_575_22mucinous adenocarcinomarenal pelvisureter |
| spellingShingle | Aparna A. N. Namshiker Amala J. Kudchadker R. G. Wiseman Pinto Primary mucinous adenocarcinoma of the ureter and renal pelvis: A case report Indian Journal of Pathology and Microbiology mucinous adenocarcinoma renal pelvis ureter |
| title | Primary mucinous adenocarcinoma of the ureter and renal pelvis: A case report |
| title_full | Primary mucinous adenocarcinoma of the ureter and renal pelvis: A case report |
| title_fullStr | Primary mucinous adenocarcinoma of the ureter and renal pelvis: A case report |
| title_full_unstemmed | Primary mucinous adenocarcinoma of the ureter and renal pelvis: A case report |
| title_short | Primary mucinous adenocarcinoma of the ureter and renal pelvis: A case report |
| title_sort | primary mucinous adenocarcinoma of the ureter and renal pelvis a case report |
| topic | mucinous adenocarcinoma renal pelvis ureter |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_575_22 |
| work_keys_str_mv | AT aparnaannamshiker primarymucinousadenocarcinomaoftheureterandrenalpelvisacasereport AT amalajkudchadker primarymucinousadenocarcinomaoftheureterandrenalpelvisacasereport AT rgwisemanpinto primarymucinousadenocarcinomaoftheureterandrenalpelvisacasereport |