Preparation and characterization of magnetic-lignin nanoparticles with potential applications for drug delivery

This study successfully combined Fe3O4 nanoparticles (made by co-precipitation technique) and lignin (extracted from sugarcane bagasse) as magnetic-lignin nanoparticles. The factors affecting the synthesis such as ratio of Fe3O4/lignin and reaction time were investigated. Fe3O4@lignin nanoparticles...

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Bibliographic Details
Main Authors: Luu Ngoc Hanh Cao, Huynh Vu Thanh Luong, Huynh Giao Dang, Quoc Phong Ho, Thi Nhu Y Vo, Thi Viet Anh Dang
Format: Article
Language:English
Published: Can Tho University Publisher 2023-11-01
Series:CTU Journal of Innovation and Sustainable Development
Subjects:
Online Access:http://web2010.thanhtoan/index.php/ctujs/article/view/625
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Summary:This study successfully combined Fe3O4 nanoparticles (made by co-precipitation technique) and lignin (extracted from sugarcane bagasse) as magnetic-lignin nanoparticles. The factors affecting the synthesis such as ratio of Fe3O4/lignin and reaction time were investigated. Fe3O4@lignin nanoparticles were obtained at optimal conditions, including the ratio between Fe3O4 and lignin of 1:0.5 and the reaction time of 9 hours. The resulting nanoparticles were spherical and had a fairly uniform particle size distribution, with an average diameter of 53.42 ± 5.12 nm (obtained from SEM images). The thermal stability of Fe3O4/lignin nanoparticles is quite stable and lignin content in hybrid Fe3O4/lignin particles is estimated to account for about 32.82%. FTIR results show a successful combination of Fe3O4 and lignin. The magnetic saturation of Fe3O4/lignin nanoparticles was determined by a vibrating sample magnetometer (VSM) with values of 50.8 emu.g-1, showed that the material keeps its super-paramagnetic properties, which is critical for their application in drug delivery field.
ISSN:2588-1418
2815-6412