Clinical Profile and Management of Patients with Newly Diagnosed Type 2 Diabetes Mellitus in Hospital Setting

Background: New-onset type 2 diabetes mellitus (T2DM) is a common clinical scenario in the hospital settings. However, data on the baseline characteristics of these patients at diagnosis in Spain remain limited. Objectives: This study aims to describe the characteristics of 165 patients admitted to...

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Main Authors: Diego Muñoz Moreno, Gilberto Pérez López, Luis Antonio Álvarez-Sala Walther, José Antonio Rueda Camino, Javier Martín Vallejo, Olga González Albarrán
Format: Article
Language:English
Published: SAGE Publishing 2025-03-01
Series:Clinical Medicine Insights: Endocrinology and Diabetes
Online Access:https://doi.org/10.1177/11795514251323831
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Summary:Background: New-onset type 2 diabetes mellitus (T2DM) is a common clinical scenario in the hospital settings. However, data on the baseline characteristics of these patients at diagnosis in Spain remain limited. Objectives: This study aims to describe the characteristics of 165 patients admitted to a Spanish tertiary hospital with new-onset T2DM. We analysed the use of different treatment regimens at discharge and metabolic control during follow-up. Methods: A retrospective, single-centre cohort study was conducted at General University Gregorio Marañón Hospital, between January 2018 and April 2021. Results: A total of 165 patients participated, with a mean age of 56.4 years, 62.4% of whom were men. Diabetes-related complications were observed in 24.8% of patients at diagnosis. Combined antidiabetic treatment was required in 87% of cases. The mean baseline HbA1c was 10.8%, which decreased by 4.9% after 8 months of follow-up. Conclusion: The clinical heterogeneity and severity of hyperglycaemia in this cohort presented management challenges, in contrast to outpatient settings. Monotherapy was rarely used, with higher adoption of SGLT-2 inhibitors and GLP-1 receptor agonists compared to other studies. Additional research is needed to refine treatment strategies and optimize care for patients with newly diagnosed T2DM.
ISSN:1179-5514