Dietary baking soda (NaHCO3) therapy recovered urolithiasis-induced kidney injury in mice by inhibition of oxidative stress, pyroptosis, and inflammation through gut-kidney axis

Dietary baking soda (NaHCO3) therapy recovered urolithiasis-induced kidney injury in mice by inhibition of oxidative stress, pyroptosis, and inflammation through gut-kidney axis

Background Urolithiasis is one of the most common urological diseases, and its incidence has increased globally in recent years. Multiple potential mechanisms are involved in urolithiasis, including renal oxidative stress, inflammatory response, fibrosis, pyroptosis, and gut microbiota disturbance....

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Main Authors: Shuai Liu, Yuchen Gao, Jun Luo, Yanhua Chen, Heng Cao, Zhuifeng Guo, Hongmin Zhou, Zhongwen Hong, Bowen Chen, Xiao Xu, Jingcheng Zhang, Nengliang Duan, Xiangcheng Zhan, Xudong Yao, Tiancheng Xie, Yunze Dong, Yunfei Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
NaHCO3
urolithiasis
NLRP3
pyroptosis
gut microbiota
gut–kidney axis
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2521456
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