Prevalence and determinants of relaparotomy in East African healthcare institutions: a systematic review and meta-analysis

Abstract Background Abdominal re-operation, or relaparotomy, refers to any repeat surgical intervention performed for intra-abdominal or wound complications during the same hospital admission or within 60 days of the initial operation. However, the regional level of relaparotomy remains unknown in E...

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Main Authors: Henok Biresaw Netsere, Yihun Miskir, Alemshet Yirga Berhie, Abebeu Tegenaw Delie, Mekedes Misiganaw Dagnaw, Daniel Mekete Alemu, Alemayehu Anley, Abdurehman Ayele, Birhanu Ayenew, Asnake Gashaw Belayneh
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Surgery
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Online Access:https://doi.org/10.1186/s12893-025-03128-9
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author Henok Biresaw Netsere
Yihun Miskir
Alemshet Yirga Berhie
Abebeu Tegenaw Delie
Mekedes Misiganaw Dagnaw
Daniel Mekete Alemu
Alemayehu Anley
Abdurehman Ayele
Birhanu Ayenew
Asnake Gashaw Belayneh
author_facet Henok Biresaw Netsere
Yihun Miskir
Alemshet Yirga Berhie
Abebeu Tegenaw Delie
Mekedes Misiganaw Dagnaw
Daniel Mekete Alemu
Alemayehu Anley
Abdurehman Ayele
Birhanu Ayenew
Asnake Gashaw Belayneh
author_sort Henok Biresaw Netsere
collection DOAJ
description Abstract Background Abdominal re-operation, or relaparotomy, refers to any repeat surgical intervention performed for intra-abdominal or wound complications during the same hospital admission or within 60 days of the initial operation. However, the regional level of relaparotomy remains unknown in East Africa. Hence, the objective of this systematic review and meta-analysis was to estimate the prevalence of relaparotomy and its associated factors in East Africa. Methods Studies were accessed through an electronic web-based search strategy from PubMed, Cochrane Library, Google Scholar, Embase, PsycINFO, and CINAHL by using a combination of search terms. The quality of each included article was assessed using criteria adapted from the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI). All statistical analyses were done using STATA version 17 software for windows, and meta-analysis was carried out using a random-effects method. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed for reporting results. Results The overall prevalence of relaparotomy was determined to be 17.36% (95% CI: 7.03–27.68; I² = 99.89%). Patients OR latency of > 60 h was 2.33 times more likely to undergo re-laparotomy compared with patients operated in < 60 h (AOR = 2.33 (95%CI [1.22–3.45)). Patients with anastomotic leak were 2 times more likely to undergo re-laparotomy compared to patients without leak (AOR = 2 (95%CI [1.35–2.64)). Older patients were 4.13 times more likely to undergo re-laparotomy compared to young patients (AOR = 4.13 (95%CI [-4.62–12.89)). Conclusion This meta-analysis provides valuable insights into the prevalence and associated factors of relaparotomy, highlighting key regional variations and patient characteristics. The study identified several factors influencing the prevalence of relaparotomy, including the duration of illness, low systolic blood pressure, anastomotic leaks, delayed surgical intervention, and age.
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spelling doaj-art-fb7263a054394cb38cfa96658d4cd9d42025-08-20T04:01:47ZengBMCBMC Surgery1471-24822025-08-012511910.1186/s12893-025-03128-9Prevalence and determinants of relaparotomy in East African healthcare institutions: a systematic review and meta-analysisHenok Biresaw Netsere0Yihun Miskir1Alemshet Yirga Berhie2Abebeu Tegenaw Delie3Mekedes Misiganaw Dagnaw4Daniel Mekete Alemu5Alemayehu Anley6Abdurehman Ayele7Birhanu Ayenew8Asnake Gashaw Belayneh9Department of Adult Health Nursing, School of Health Science, College of Medicine and Health Science, Bahir Dar UniversityDepartment of Emergency and Critical Care Nursing, College of Medicine Health Science, Bahir Dar UniversityDepartment of Adult Health Nursing, School of Health Science, College of Medicine and Health Science, Bahir Dar UniversityDepartment of Adult Health Nursing, School of Health Science, College of Medicine and Health Science, Bahir Dar UniversityDepartment of Adult Health Nursing, School of Health Science, College of Medicine and Health Science, Bahir Dar UniversityDepartment of Reproductive Health and Population Studies, School of Public Health, College of Medicine and Health Sciences, Bahir Dar UniversityDepartment of Adult Health Nursing, College of Medicine and Health Science, Arba Minch UniversityDepartment of Adult Health Nursing, College of Medicine and Health Science, Arba Minch UniversityDepartment of Adult Health Nursing, College of Health Science, Assosa UniversityDepartment of Emergency and Critical Care Nursing, College of Medicine Health Science, Bahir Dar UniversityAbstract Background Abdominal re-operation, or relaparotomy, refers to any repeat surgical intervention performed for intra-abdominal or wound complications during the same hospital admission or within 60 days of the initial operation. However, the regional level of relaparotomy remains unknown in East Africa. Hence, the objective of this systematic review and meta-analysis was to estimate the prevalence of relaparotomy and its associated factors in East Africa. Methods Studies were accessed through an electronic web-based search strategy from PubMed, Cochrane Library, Google Scholar, Embase, PsycINFO, and CINAHL by using a combination of search terms. The quality of each included article was assessed using criteria adapted from the Joanna Briggs Institute Meta-Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI). All statistical analyses were done using STATA version 17 software for windows, and meta-analysis was carried out using a random-effects method. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed for reporting results. Results The overall prevalence of relaparotomy was determined to be 17.36% (95% CI: 7.03–27.68; I² = 99.89%). Patients OR latency of > 60 h was 2.33 times more likely to undergo re-laparotomy compared with patients operated in < 60 h (AOR = 2.33 (95%CI [1.22–3.45)). Patients with anastomotic leak were 2 times more likely to undergo re-laparotomy compared to patients without leak (AOR = 2 (95%CI [1.35–2.64)). Older patients were 4.13 times more likely to undergo re-laparotomy compared to young patients (AOR = 4.13 (95%CI [-4.62–12.89)). Conclusion This meta-analysis provides valuable insights into the prevalence and associated factors of relaparotomy, highlighting key regional variations and patient characteristics. The study identified several factors influencing the prevalence of relaparotomy, including the duration of illness, low systolic blood pressure, anastomotic leaks, delayed surgical intervention, and age.https://doi.org/10.1186/s12893-025-03128-9RelaparotomyPrevalenceDeterminantsEast Africa
spellingShingle Henok Biresaw Netsere
Yihun Miskir
Alemshet Yirga Berhie
Abebeu Tegenaw Delie
Mekedes Misiganaw Dagnaw
Daniel Mekete Alemu
Alemayehu Anley
Abdurehman Ayele
Birhanu Ayenew
Asnake Gashaw Belayneh
Prevalence and determinants of relaparotomy in East African healthcare institutions: a systematic review and meta-analysis
BMC Surgery
Relaparotomy
Prevalence
Determinants
East Africa
title Prevalence and determinants of relaparotomy in East African healthcare institutions: a systematic review and meta-analysis
title_full Prevalence and determinants of relaparotomy in East African healthcare institutions: a systematic review and meta-analysis
title_fullStr Prevalence and determinants of relaparotomy in East African healthcare institutions: a systematic review and meta-analysis
title_full_unstemmed Prevalence and determinants of relaparotomy in East African healthcare institutions: a systematic review and meta-analysis
title_short Prevalence and determinants of relaparotomy in East African healthcare institutions: a systematic review and meta-analysis
title_sort prevalence and determinants of relaparotomy in east african healthcare institutions a systematic review and meta analysis
topic Relaparotomy
Prevalence
Determinants
East Africa
url https://doi.org/10.1186/s12893-025-03128-9
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