Treatment with a Monoclonal Anti-IL-12p40 Antibody Induces Substantial Gut Microbiota Changes in an Experimental Colitis Model
Background and Aim. Crohn’s disease is associated with gut microbiota (GM) dysbiosis. Treatment with the anti-IL-12p40 monoclonal antibody (12p40-mAb) has therapeutic effect in Crohn’s disease patients. This study addresses whether a 12p40-mAb treatment influences gut microbiota (GM) composition in...
Saved in:
| Main Authors: | Josué Castro-Mejía, Maja Jakesevic, Łukasz Krych, Dennis S. Nielsen, Lars H. Hansen, Bodil C. Sondergaard, Peter H. Kvist, Axel K. Hansen, Thomas L. Holm |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
|
| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/4953120 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Oral LPS Dosing Induces Local Immunological Changes in the Pancreatic Lymph Nodes in Mice
by: Pernille Kihl, et al.
Published: (2019-01-01) -
Evaluating IL-21 as a Potential Therapeutic Target in Crohn’s Disease
by: Thomas Lindebo Holm, et al.
Published: (2018-01-01) -
Concurrent Ocular and Cerebral Toxoplasmosis in a Liver Transplant Patient Treated with Anti-CD40 Monoclonal Antibody
by: Roos Van Den Noortgate, et al.
Published: (2023-01-01) -
De novo clustering of long-read amplicons improves phylogenetic insight into microbiome data
by: Yan Hui, et al.
Published: (2025-12-01) -
Short communication: Substantial heritability of larval size in the black soldier fly reveals potential for selective breeding
by: R.M. Zaalberg, et al.
Published: (2025-06-01)